finding_genes_of_interest_with_panther_hmms
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Table of Contents
Finding genes of interest with PANTHER HMMs
By Joran Martijn (Sep 2023)
The PANTHER database
The PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System was designed to classify proteins (and their genes) in order to facilitate high-throughput analysis. The goal of PANTHER is to classify proteins by function.
The PANTHER initiative started in 1998 and was the first online database that included protein phylogenetic trees. Initially, very few species had whole genome sequences available but starting with version 6 (released in 2006), many more species were added. PANTHER16 (or 17?) included 142 fully sequenced genomes, including 19 vertebrates, 15 invertebrates, 14 fungi, 40 plants, 11 other eukaryotes, 8 archaea and 35 bacteria. The list is thus fairly limited and, more focused towards non-protist eukaryotes.
In 2002, PANTHER3 had 271779 proteins over 6155 families. In 2020, PANTHER16 had 2063337 proteins over 15635 families.
PANTHER families are defined as clusters of related proteins for which a good multiple sequence alignment can be made (defined in their original 2003 paper ). The emphasis is thus not so much on trying to reconstruct exact, complete orthogroups, but rather groupings that are useful to predict protein function on new protein sequences.
A key aspect of the PANTHER database is the division of families into multiple subfamilies. PANTHER's focus is on function and to a lesser degree evolutionary history, hence they attempt to classify proteins with distinct functions into distinct subfamilies. The idea is thus that each different subfamily has a distinct function.
The splitting of families into subfamilies was initially I think mostly done manually by trained biologists. However, in the most recent versions, it seems to be a mostly automated process but with the results still curated by trained biologists. In the 2021 paper a subfamily is defined as follows
A subfamily roughly corresponds to a group of least diverged orthologs, in that most members of each subfamily are mutually least diverged orthologs of all other members of the subfamily
I find this definition a bit cryptic, but it becomes a bit clearer with the visual example that they provide in the 2021 paper.
Here, sequences from distinct subfamilies are given a different color (blue, red, brown, pink, green). Speciation events are marked with green circles, duplication events with orange circles. Triangles are collapsed nodes, and diamonds indicate the root nodes of distinct subfamilies.
What becomes immediately apparent is that subfamilies are not necessary monophyletic! For example, the blue subfamily are polyphyletic (or paraphyletic?).
This is because of a duplication event that happened in the bottom daughter of the global root node. Two branches flow from the duplication event: a shorter one and a longer one. In PANTHERs definition, the sequences emerging from the shorter one comprise the least diverged orthologs (orthologs relative to the DANRE/ORYLA lineage on the top of the figure), and thus they belong to the same subfamily as the DANRE/ORYLA proteins. The sequences emerging from the longer one are thus NOT the least diverged, and hence they belong to a distinct subfamily.
Thus, any time a duplication event happens, a new subfamily is spawned. The exception is when the duplication leads to in-paralogs, or technically more specifically, to within-genome paralogs. That is why the duplication to the ORYLA and ORNAN copies did not spawn new subfamilies. The implication here is thus that after a duplication, one of the copies evolves to assume a new functional role.
Each family and subfamily in the database has associated with it a MSA, a tree and an HMM. The HMMs are useful to detect orthologs of these families and subfamilies in your pet genome. It is also useful to compare the E-values / bit-scores between families and subfamilies. If a novel predicted protein from your pet genome scores more highly against a family than a subfamily, it may indicate that your protein represents a novel subfamily.
PANTHER on Perun
Currently, the PANTHER17 database is stored on Perun here /scratch3/rogerlab_databases/other_dbs/PANTHER17.0/. It contains two subdirectories, books/ and globals/. The globals directory contains the actual database of HMMs, binHmm.* files, and names.tab, a file containing the actual annotation of each family and subfamily. Let's take a closer look:
PTHR10000.mag.mod PHOSPHOSERINE PHOSPHATASE PTHR10000.SF55.mod 5-AMINO-6-(5-PHOSPHO-D-RIBITYLAMINO)URACIL PHOSPHATASE YCSE PTHR10000.SF23.mod 5-AMINO-6-(5-PHOSPHO-D-RIBITYLAMINO)URACIL PHOSPHATASE YITU PTHR10000.SF57.mod KANOSAMINE-6-PHOSPHATE PHOSPHATASE ... ... PTHR10000.SF56.mod MANNOSYL-3-PHOSPHOGLYCERATE PHOSPHATASE PTHR10003.mag.mod SUPEROXIDE DISMUTASE CU-ZN -RELATED PTHR10003.SF95.mod SUPEROXIDE DISMUTASE [CU-ZN] 2, CHLOROPLASTIC PTHR10003.SF82.mod SOD_CU DOMAIN-CONTAINING PROTEIN PTHR10003.SF94.mod EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN] 3 PTHR10003.SF31.mod SUPEROXIDE DISMUTASE [CU-ZN] 3 ... ...
Those ending with .mag.mod are families, and those ending with .SF[number].mod are their respective subfamilies.
The Light_panther17.tsv file is a simple list of all families.
Searching your genome for PANTHER families homologs
Do an hmmscan
Simply do an hmmscan from the HMMER3 package. hmmscan takes as a query a single or a list of protein sequences and compares them with a database of HMM profiles. Below, we are taking the entire PANTHER17 database of HMMs as a database.
hmmscan \ -E 0.001 --incE 0.0001 \ --domE 0.01 --incdomE 0.01 \ --notextw --cpu 10 \ --tblout ergo_vs_panther17.tblout --domtblout ergo_vs_panther17.domtblout binHmm Ergobibamus_cyprinoides_CL.proteins.fa
This will yield two outfiles, the ergo_vs_panther17.tblout and ergo_vs_panther17.domtblout.
The .tblout file is a tabular output file where each line has a unique query (a protein sequence) and target (the HMM profile) combination. The overall E-value and score between HMM and sequence are reported (“full sequence”), as well as the segment of the protein that scored the highest with said HMM (“best 1 domain”), as well as a bunch of metrics for estimating the number of “domains”.
# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target # ------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PTHR31752.SF18.pir - FUN_000001-T1 - 6.8e-23 83.9 5.0 3.3e-12 48.7 2.4 2.1 1 1 1 2 2 2 2 - PTHR36838.orig.30.pir - FUN_000001-T1 - 5.6e-22 81.0 13.0 7e-22 80.7 1.8 2.2 2 0 0 2 2 2 2 - PTHR36838.SF1.pir - FUN_000001-T1 - 1.9e-19 72.8 4.4 1.9e-19 72.8 4.4 2.4 2 0 0 2 2 1 1 - PTHR31752.orig.30.pir - FUN_000001-T1 - 3.3e-16 62.0 4.6 2.6e-14 55.7 4.6 2.2 1 1 0 1 1 1 1 - PTHR36838.SF3.pir - FUN_000001-T1 - 1.4e-12 50.3 3.7 2.6e-12 49.3 0.1 2.2 2 0 0 2 2 1 1 - PTHR31752.SF40.pir - FUN_000001-T1 - 1.2e-11 47.3 0.0 2e-11 46.6 0.0 1.3 1 0 0 1 1 1 1 - PTHR31752.SF2.pir - FUN_000001-T1 - 5.5e-09 38.3 0.0 7e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 - PTHR31752.SF49.pir - FUN_000001-T1 - 3.4e-08 35.9 0.0 5.9e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 - ...
NOTE that the outfile uses the word “domain” because traditionally HMM profiles describe protein domains. The Pfam is a good example of a database of domain HMM profiles. PANTHER HMM describes entire proteins. Hence the term 'domain' is not very well suited here, and can be a bit confusing.
NOTE also that the names of the families are slightly different here. Instead of ending with .mag.mod or .SF[number].mod, they end with .orig.30.pir and .SF[number].pir.
A protein sequence may have multiple segments that each match well with a particular HMM profile independently. To see each of these alignments separately, we can inspect the .domtblout file:
# --- full sequence --- -------------- this domain ------------- hmm coord ali coord env coord # target name accession tlen query name accession qlen E-value score bias # of c-Evalue i-Evalue score bias from to from to from to acc description of target # ------------------- ---------- ----- -------------------- ---------- ----- --------- ------ ----- --- --- --------- --------- ------ ----- ----- ----- ----- ----- ----- ----- ---- --------------------- PTHR31752.SF18.pir - 418 FUN_000001-T1 - 412 6.8e-23 83.9 5.0 1 2 1.9e-16 3.3e-12 48.7 2.4 9 167 10 174 4 201 0.78 - PTHR31752.SF18.pir - 418 FUN_000001-T1 - 412 6.8e-23 83.9 5.0 2 2 1.4e-12 2.4e-08 35.9 0.0 261 369 210 350 182 404 0.72 - PTHR36838.orig.30.pir - 308 FUN_000001-T1 - 412 5.6e-22 81.0 13.0 1 2 4e-26 7e-22 80.7 1.8 10 214 15 272 9 281 0.82 - PTHR36838.orig.30.pir - 308 FUN_000001-T1 - 412 5.6e-22 81.0 13.0 2 2 0.0028 50 5.6 3.8 222 276 310 367 301 398 0.80 - PTHR36838.SF1.pir - 308 FUN_000001-T1 - 412 1.9e-19 72.8 4.4 1 1 1.1e-23 1.9e-19 72.8 4.4 9 211 14 269 8 276 0.82 - PTHR31752.orig.30.pir - 405 FUN_000001-T1 - 412 3.3e-16 62.0 4.6 1 1 1.4e-18 2.6e-14 55.7 4.6 10 340 10 330 3 402 0.73 - PTHR36838.SF3.pir - 312 FUN_000001-T1 - 412 1.4e-12 50.3 3.7 1 1 1.5e-16 2.6e-12 49.3 0.1 10 216 16 272 10 279 0.77 - PTHR31752.SF40.pir - 360 FUN_000001-T1 - 412 1.2e-11 47.3 0.0 1 1 1.1e-15 2e-11 46.6 0.0 37 267 36 274 8 282 0.75 - PTHR31752.SF2.pir - 349 FUN_000001-T1 - 412 5.5e-09 38.3 0.0 1 1 4e-13 7e-09 38.0 0.0 103 284 105 332 60 400 0.70 - ...
Now, each line represents a unique “domain” (i.e. segment of a protein sequence) and HMM profile combination. The overall E-value and score between HMM and the full sequence is still reported, as well as the scores of the specific “domains” that were found for each sequence.
Add HMM profile coverage information
You may want to reduce the number of false positives (i.e. protein sequences that match with an HMM but are not really orthologs) by discarding queries that only have partial alignments with the HMM. With BLAST I like to use the fields qcovhsp, qcovs, which describe how much of the query was covered by the HSP (High scoring Segment Pair, or in simpler terms, the alignment between query and hit) (qcovhsp) or collection of alignments between the same query and hit (qcovs). For example, if an alignment covered less than, say 60% of the length of the query, I may consider it a false positive hit. Unfortunately, HMMER does not directly report such metrics, but it does report the metrics necessary to calculate them. I wrote a python script, extend_hmmer_domtblout.py that does exactly this:
extend_hmmer_domtblout.py -m hmmscan -i ergo_vs_panther17.domtblout -o ergo_vs_panther17.ext.domtblout
This yields a file that looks like this
TargetName TargetAcc TargetLen QueryName QueryAcc QueryLen seq-E-value seq-Score seq-Bias dom-No dom-Count dom-c-Evalue dom-i-Evalue dom-Score dom-Bias hmm-From hmm-To ali-From ali-To env-From env-To mean-PP DescriptionOfTarget qcovhsp tcovhsp qcovs tcovs PTHR31752.SF18.pir - 418 FUN_000001-T1 - 412 6.8e-23 83.9 5.0 1 2 1.9e-16 3.3e-12 48.7 2.4 9 167 10 174 4 201 0.78 - 0.40 0.38 0.74 0.64 PTHR31752.SF18.pir - 418 FUN_000001-T1 - 412 6.8e-23 83.9 5.0 2 2 1.4e-12 2.4e-08 35.9 0.0 261 369 210 350 182 404 0.72 - 0.34 0.26 0.74 0.64 PTHR36838.orig.30.pir - 308 FUN_000001-T1 - 412 5.6e-22 81.0 13.0 1 2 4e-26 7e-22 80.7 1.8 10 214 15 272 9 281 0.82 - 0.63 0.67 0.77 0.84 PTHR36838.orig.30.pir - 308 FUN_000001-T1 - 412 5.6e-22 81.0 13.0 2 2 0.0028 50.0 5.6 3.8 222 276 310 367 301 398 0.8 - 0.14 0.18 0.77 0.84 PTHR36838.SF1.pir - 308 FUN_000001-T1 - 412 1.9e-19 72.8 4.4 1 1 1.1e-23 1.9e-19 72.8 4.4 9 211 14 269 8 276 0.82 - 0.62 0.66 0.62 0.66 PTHR31752.orig.30.pir - 405 FUN_000001-T1 - 412 3.3e-16 62.0 4.6 1 1 1.4e-18 2.6e-14 55.7 4.6 10 340 10 330 3 402 0.73 - 0.78 0.82 0.78 0.82 PTHR36838.SF3.pir - 312 FUN_000001-T1 - 412 1.4e-12 50.3 3.7 1 1 1.5e-16 2.6e-12 49.3 0.1 10 216 16 272 10 279 0.77 - 0.62 0.66 0.62 0.66 PTHR31752.SF40.pir - 360 FUN_000001-T1 - 412 1.2e-11 47.3 0.0 1 1 1.1e-15 2e-11 46.6 0.0 37 267 36 274 8 282 0.75 - 0.58 0.64 0.58 0.64 PTHR31752.SF2.pir - 349 FUN_000001-T1 - 412 5.5e-09 38.3 0.0 1 1 4e-13 7e-09 38.0 0.0 103 284 105 332 60 400 0.7 - 0.55 0.52 0.55 0.52 PTHR31752.SF49.pir - 358 FUN_000001-T1 - 412 3.4e-08 35.9 0.0 1 1 3.3e-12 5.9e-08 35.2 0.0 39 309 38 319 6 370 0.72 - 0.68 0.76 0.68 0.76 PTHR31913.orig.30.pir - 655 FUN_000003-T1 - 778 1e-54 189.4 0.0 1 1 7.2e-59 2e-54 188.4 0.0 203 649 350 776 296 778 0.83 - 0.55 0.68 0.55 0.68 PTHR31913.SF0.pir - 659 FUN_000003-T1 - 778 8e-54 186.4 0.0 1 1 5.1e-58 1.4e-53 185.6 0.0 313 653 441 776 332 778 0.88 - 0.43 0.52 0.43 0.52 PTHR31913.SF7.pir - 619 FUN_000003-T1 - 778 7.6e-15 57.4 0.0 1 1 4.9e-19 1.4e-14 56.6 0.0 325 551 516 730 506 739 0.85 - 0.28 0.37 0.28 0.37 ...
The script does a few things. It reformats the header line, and it makes the whole table tab delimited, which makes it easier to parse later on. Most importantly, it adds 4 new columns, qcovhsp, tcovhsp, qcovs and tcovs.
qcovhsp how much of the query (the protein sequence) is covered by the HMM:protein alignment tcovhsp how much of the target (the HMM profile) is covered by the HMM:protein alignment qcovs how much of the query (the protein sequence) is covered _in_total_ by all HMM:protein alignments between this HMM and this protein tcovs how much of the target (the HMM profile) is covered _in_total_ by all HMM:protein alignments between this HMM and this protein
The qcovs and tcovs metrics are particularly useful when working with PANTHER HMM-profiles because of the nature of these profiles. Since they describe entire proteins, and not just single domains, a true but distant ortholog of the PANTHER family may not align well over the entire profile. Poorly conserved regions, such as those in between conserved domains (i.e. 'linker' regions) tend to prematurely break the alignment between protein and profile. Thus, we'd get two significant hits, one with the first part of the profile, and one with the second part of the profile. The qcovs and tcovs thus take into account both alignments, whereas the qcovhsp and tcovhsp do not.
Add PANTHER annotation
Knowing which families and subfamilies had hits in your genome is nice and all, but it's just a bunch of unintelligible identifiers. I wrote another script that links these identifiers with their actual annotations (this linking information is found in names.tab and adds the actual annotations to the .domtblout file
add_pthr_annotation_to_hmmer_out.py -i ergo_vs_panther17.ext.domtblout -n names.tab > ergo_vs_panther17.annot.ext.domtblout
The output file will look something like this
TargetName TargetAcc TargetLen QueryName QueryAcc QueryLen seq-E-value seq-Score seq-Bias dom-No dom-Count dom-c-Evalue dom-i-Evalue dom-Score dom-Bias hmm-From hmm-To ali-From ali-To env-From env-To mean-PP DescriptionOfTarget qcovhsp tcovhsp qcovs tcovs annotation PTHR31752.SF18.pir - 418 FUN_000001-T1 - 412 6.8e-23 83.9 5.0 1 2 1.9e-16 3.3e-12 48.7 2.4 9 167 10 174 4 201 0.78 - 0.40 0.38 0.74 0.64 AUXIN_EFFLUX_CARRIER_COMPONENT_3A PTHR31752.SF18.pir - 418 FUN_000001-T1 - 412 6.8e-23 83.9 5.0 2 2 1.4e-12 2.4e-08 35.9 0.0 261 369 210 350 182 404 0.72 - 0.34 0.26 0.74 0.64 AUXIN_EFFLUX_CARRIER_COMPONENT_3A PTHR36838.orig.30.pir - 308 FUN_000001-T1 - 412 5.6e-22 81.0 13.0 1 2 4e-26 7e-22 80.7 1.8 10 214 15 272 9 281 0.82 - 0.63 0.67 0.77 0.84 AUXIN_EFFLUX_CARRIER_FAMILY_PROTEIN PTHR36838.orig.30.pir - 308 FUN_000001-T1 - 412 5.6e-22 81.0 13.0 2 2 0.0028 50.0 5.6 3.8 222 276 310 367 301 398 0.8 - 0.14 0.18 0.77 0.84 AUXIN_EFFLUX_CARRIER_FAMILY_PROTEIN PTHR36838.SF1.pir - 308 FUN_000001-T1 - 412 1.9e-19 72.8 4.4 1 1 1.1e-23 1.9e-19 72.8 4.4 9 211 14 269 8 276 0.82 - 0.62 0.66 0.62 0.66 SLR1864_PROTEIN PTHR31752.orig.30.pir - 405 FUN_000001-T1 - 412 3.3e-16 62.0 4.6 1 1 1.4e-18 2.6e-14 55.7 4.6 10 340 10 330 3 402 0.73 - 0.78 0.82 0.78 0.82 AUXIN_EFFLUX_CARRIER_COMPONENT_1B-RELATED PTHR36838.SF3.pir - 312 FUN_000001-T1 - 412 1.4e-12 50.3 3.7 1 1 1.5e-16 2.6e-12 49.3 0.1 10 216 16 272 10 279 0.77 - 0.62 0.66 0.62 0.66 AUXIN_EFFLUX_CARRIER_FAMILY_PROTEIN PTHR31752.SF40.pir - 360 FUN_000001-T1 - 412 1.2e-11 47.3 0.0 1 1 1.1e-15 2e-11 46.6 0.0 37 267 36 274 8 282 0.75 - 0.58 0.64 0.58 0.64 AUXIN_EFFLUX_CARRIER_COMPONENT_8 PTHR31752.SF2.pir - 349 FUN_000001-T1 - 412 5.5e-09 38.3 0.0 1 1 4e-13 7e-09 38.0 0.0 103 284 105 332 60 400 0.7 - 0.55 0.52 0.55 0.52 AUXIN_EFFLUX_CARRIER_COMPONENT_5 PTHR31752.SF49.pir - 358 FUN_000001-T1 - 412 3.4e-08 35.9 0.0 1 1 3.3e-12 5.9e-08 35.2 0.0 39 309 38 319 6 370 0.72 - 0.68 0.76 0.68 0.76 AUXIN_EFFLUX_CARRIER_COMPONENT PTHR31913.orig.30.pir - 655 FUN_000003-T1 - 778 1e-54 189.4 0.0 1 1 7.2e-59 2e-54 188.4 0.0 203 649 350 776 296 778 0.83 - 0.55 0.68 0.55 0.68 VACUOLAR_IMPORT_AND_DEGRADATION_PROTEIN_27 PTHR31913.SF0.pir - 659 FUN_000003-T1 - 778 8e-54 186.4 0.0 1 1 5.1e-58 1.4e-53 185.6 0.0 313 653 441 776 332 778 0.88 - 0.43 0.52 0.43 0.52 VACUOLAR_IMPORT_AND_DEGRADATION_PROTEIN_27 PTHR31913.SF7.pir - 619 FUN_000003-T1 - 778 7.6e-15 57.4 0.0 1 1 4.9e-19 1.4e-14 56.6 0.0 325 551 516 730 506 739 0.85 - 0.28 0.37 0.28 0.37 DEM_PROTEIN PTHR31913.SF5.pir - 613 FUN_000003-T1 - 778 2.3e-12 49.0 0.1 1 1 5.5e-16 1.5e-11 46.2 0.1 231 539 442 731 434 740 0.78 - 0.37 0.50 0.37 0.50 VID27_DOMAIN-CONTAINING_PROTEIN PTHR31913.SF2.pir - 622 FUN_000003-T1 - 778 4.1e-08 35.1 0.0 1 1 1.4e-11 3.9e-07 31.9 0.0 325 553 516 729 506 738 0.77 - 0.28 0.37 0.28 0.37 OS02G0789600_PROTEIN PTHR23359.SF250.pir - 270 FUN_000004-T1 - 520 7.6e-74 251.2 0.0 1 2 3.2e-74 7.2e-71 241.4 0.0 59 265 48 262 21 267 0.93 - 0.41 0.77 0.45 0.77 KINASE,_PUTATIVE-RELATED ...
Filter by HMM profile coverage and composition bias
You may only want to keep proteins of your pet genome that are (nearly) fully covered by PANTHER (sub)families to reduce the number of false positives.
I did this by only keeping lines of the .domtblout where the tcovs (the coverage of the target accumulated over all protein:HMM-profile alignments; the 27th column) is at least 50% of the HMM-profile length, and the seq-Bias score (9th column) is less than 90% of the total bit seq-Score (8th column).
After that, the table is sorted by protein sequence identifier and only the best hit, according to seq-Score remains.
function body {
IFS= read -r header
printf '%s\n' "$header"
"$@"
}
cat ergo_vs_panther17.annot.ext.domtblout \
| body awk '$27>=0.50 && $9/$8<0.9' \
| body sort -k4,4 -k8,8nr \
| body sort -k4,4 -u \
> ergo_vs_panther17.filt.ext.domtblout
The body function is a nifty trick to only apply your awk or sort operations on the body of the table and leave the header intact.
Our new file looks as follows:
TargetName TargetAcc TargetLen QueryName QueryAcc QueryLen seq-E-value seq-Score seq-Bias dom-No dom-Count dom-c-Evalue dom-i-Evalue dom-Score dom-Bias hmm-From hmm-To ali-From ali-To env-From env-To mean-PP DescriptionOfTarget qcovhsp tcovhsp qcovs tcovs annotation PTHR31752.SF18.pir - 418 FUN_000001-T1 - 412 6.8e-23 83.9 5.0 1 2 1.9e-16 3.3e-12 48.7 2.4 9 167 10 174 4 201 0.78 - 0.40 0.38 0.74 0.64 AUXIN_EFFLUX_CARRIER_COMPONENT_3A PTHR31913.orig.30.pir - 655 FUN_000003-T1 - 778 1e-54 189.4 0.0 1 1 7.2e-59 2e-54 188.4 0.0 203 649 350 776 296 778 0.83 - 0.55 0.68 0.55 0.68 VACUOLAR_IMPORT_AND_DEGRADATION_PROTEIN_27 PTHR23359.SF250.pir - 270 FUN_000004-T1 - 520 7.6e-74 251.2 0.0 1 2 3.2e-74 7.2e-71 241.4 0.0 59 265 48 262 21 267 0.93 - 0.41 0.77 0.45 0.77 KINASE,_PUTATIVE-RELATED PTHR45991.orig.30.pir - 450 FUN_000005-T1 - 544 9.4e-99 334.2 0.0 1 1 2e-101 1.3e-98 333.8 0.0 32 438 18 505 11 520 0.86 - 0.90 0.90 0.90 0.90 PACHYTENE_CHECKPOINT_PROTEIN_2 PTHR13563.orig.30.pir - 346 FUN_000006-T1 - 343 8.1e-52 179.5 0.0 1 1 3.6e-56 1e-51 179.1 0.0 63 321 43 320 20 343 0.79 - 0.81 0.75 0.81 0.75 TRNA_(GUANINE-9-)_METHYLTRANSFERASE PTHR11685.SF436.pir - 285 FUN_000007-T1 - 589 2.4e-19 72.8 8.5 1 1 5.8e-23 2.6e-19 72.6 8.5 76 240 241 491 132 578 0.7 - 0.43 0.58 0.43 0.58 RBR-TYPE_E3_UBIQUITIN_TRANSFERASE PTHR46233.orig.30.pir - 231 FUN_000011-T1 - 208 1.7e-48 167.7 0.0 1 1 5.2e-52 2.1e-48 167.4 0.0 20 214 11 206 3 207 0.94 - 0.94 0.84 0.94 0.84 HYDROXYACYLGLUTATHIONE_HYDROLASE_GLOC PTHR23102.SF19.pir - 206 FUN_000013-T1 - 233 1e-31 113.1 9.9 1 1 1.1e-35 1.3e-31 112.7 9.9 58 172 38 151 31 186 0.9 - 0.49 0.56 0.49 0.56 CLEAVAGE_AND_POLYADENYLATION_SPECIFICITY_FACTOR_SUBUNIT_4-LIKE_PROTEIN-RELATED PTHR47979.SF50.pir - 216 FUN_000014-T1 - 206 1.6e-105 353.9 0.0 1 1 8.5e-108 1.9e-105 353.7 0.0 1 193 1 193 1 204 0.98 - 0.94 0.89 0.94 0.89 RAS-RELATED_PROTEIN_RAB-2B PTHR17605.orig.30.pir - 732 FUN_000016-T1 - 712 4.8e-175 586.8 0.0 1 1 1e-177 6.9e-175 586.3 0.0 151 729 100 710 92 712 0.92 - 0.86 0.79 0.86 0.79 RIBOSOME_BIOGENESIS_PROTEIN_BOP1__BLOCK_OF_PROLIFERATION_1_PROTEIN ...
Each of the protein queries in this list has a significant hit against a PANTHER family, and all the alignments between this protein and the HMM-profile cumulatively cover at least 50% of the HMM-profile.
Selecting (sub)families of interest
Until now we have considered all predicted proteins of our pet genome. But perhaps we are only particularly interested for whatever reason in a subset of them.
For example, we want to know what kind of energy conservation genes are present in our genome. From studying the literature, I've compiled in families_of_interest.ATP.upd.list the following list of PANTHER families that seem to be involved in ATP synthesis. The table is formatted like “category long name”, “category short name”, “gene or protein name”, “PANTHER family identifier (names.tab)”, “PANTHER family annotation”, “PANTHER family identifier (binHmm database)”.
ENERGY_CONSERVATION ATP ME PTHR23406.mag.mod MALIC_ENZYME-RELATED PTHR23406.orig.30.pir ENERGY_CONSERVATION ATP ME PTHR23406.SF32.mod NADP-DEPENDENT_MALIC_ENZYME PTHR23406.SF32.pir ENERGY_CONSERVATION ATP PNO/PFO PTHR32154.mag.mod PYRUVATE-FLAVODOXIN_OXIDOREDUCTASE-RELATED PTHR32154.orig.30.pir ENERGY_CONSERVATION ATP PNO/PFO PTHR32154.SF0.mod PYRUVATE-FLAVODOXIN_OXIDOREDUCTASE-RELATED PTHR32154.SF0.pir ENERGY_CONSERVATION ATP Adrenodoxin/Ferredoxin_Yah1 PTHR23426.mag.mod FERREDOXIN/ADRENODOXIN PTHR23426.orig.30.pir ENERGY_CONSERVATION ATP Adrenodoxin/Ferredoxin_Yah1 PTHR23426.SF65.mod FERREDOXIN_1-RELATED PTHR23426.SF65.pir ENERGY_CONSERVATION ATP FdxR/Arh1 PTHR11938.mag.mod FAD_NADPH_DEHYDROGENASE/OXIDOREDUCTASE PTHR11938.orig.30.pir ENERGY_CONSERVATION ATP FdxR/Arh1 PTHR11938.SF91.mod NADPH:ADRENODOXIN_OXIDOREDUCTASE,_MITOCHONDRIAL PTHR11938.SF91.pir ENERGY_CONSERVATION ATP HydA PTHR11615.mag.mod NITRATE,_FORMATE,_IRON_DEHYDROGENASE PTHR11615.orig.30.pir ENERGY_CONSERVATION ATP HydA-1 PTHR11615.SF345.mod CATALYTIC_SUBUNIT_OF_IRON-ONLY_HYDROGENASE-RELATED PTHR11615.SF345.pir ENERGY_CONSERVATION ATP HydA-4 PTHR11615.SF304.mod IRON_HYDROGENASE,_PUTATIVE-RELATED PTHR11615.SF304.pir ENERGY_CONSERVATION ATP HydE PTHR43726.mag.mod 3-METHYLORNITHINE_SYNTHASE PTHR43726.orig.30.pir ENERGY_CONSERVATION ATP HydE PTHR43726.SF1.mod [FEFE]_HYDROGENASE_MATURASE_SUBUNIT_HYDE PTHR43726.SF1.pir ENERGY_CONSERVATION ATP HydF PTHR42714.mag.mod TRNA_MODIFICATION_GTPASE_GTPBP3 PTHR42714.orig.30.pir ENERGY_CONSERVATION ATP HydF PTHR42714.SF6.mod TRANSLATION_INITIATION_FACTOR_IF-2 PTHR42714.SF6.pir ENERGY_CONSERVATION ATP HydG PTHR43583.mag.mod 2-IMINOACETATE_SYNTHASE PTHR43583.orig.30.pir ENERGY_CONSERVATION ATP HydG PTHR43583.SF2.mod BIOTIN_AND_THIAMIN_SYNTHESIS_ASSOCIATED_DOMAIN_CONTAINING_PROTEIN PTHR43583.SF2.pir ENERGY_CONSERVATION ATP NuoF/Complex_I_51kDa PTHR11780.mag.mod NADH-UBIQUINONE_OXIDOREDUCTASE_FLAVOPROTEIN_1_NDUFV1 PTHR11780.orig.30.pir ENERGY_CONSERVATION ATP NuoF/Complex_I_51kDa PTHR11780.SF10.mod NADH_DEHYDROGENASE_[UBIQUINONE]_FLAVOPROTEIN_1,_MITOCHONDRIAL PTHR11780.SF10.pir ENERGY_CONSERVATION ATP NuoE/Complex_I_24kDa PTHR10371.mag.mod NADH_DEHYDROGENASE_UBIQUINONE_FLAVOPROTEIN_2,_MITOCHONDRIAL PTHR10371.orig.30.pir ENERGY_CONSERVATION ATP NuoE/Complex_I_24kDa PTHR10371.SF3.mod NADH_DEHYDROGENASE_[UBIQUINONE]_FLAVOPROTEIN_2,_MITOCHONDRIAL PTHR10371.SF3.pir ENERGY_CONSERVATION ATP ASCT-1B PTHR21432.mag.mod ACETYL-COA_HYDROLASE-RELATED PTHR21432.orig.30.pir ENERGY_CONSERVATION ATP ASCT-1B PTHR21432.SF20.mod ACETYL-COA_DEACYLASE PTHR21432.SF20.pir ENERGY_CONSERVATION ATP ASCT-1C PTHR43609.mag.mod ACETYL-COA_HYDROLASE PTHR43609.orig.30.pir ENERGY_CONSERVATION ATP ASCT-1C PTHR43609.SF1.mod ACETYL-COA_HYDROLASE PTHR43609.SF1.pir ENERGY_CONSERVATION ATP SCSa/STKa PTHR11117.mag.mod SUCCINYL-COA_LIGASE_SUBUNIT_ALPHA PTHR11117.orig.30.pir ENERGY_CONSERVATION ATP SCSa/STKa PTHR11117.SF2.mod SUCCINATE--COA_LIGASE_[ADP/GDP-FORMING]_SUBUNIT_ALPHA,_MITOCHONDRIAL PTHR11117.SF2.pir ENERGY_CONSERVATION ATP SCSb/STKb PTHR11815.mag.mod SUCCINYL-COA_SYNTHETASE_BETA_CHAIN PTHR11815.orig.30.pir ENERGY_CONSERVATION ATP SCSb/STKb PTHR11815.SF10.mod SUCCINATE--COA_LIGASE_[GDP-FORMING]_SUBUNIT_BETA,_MITOCHONDRIAL PTHR11815.SF10.pir ENERGY_CONSERVATION ATP DLDH PTHR43716.mag.mod D-2-HYDROXYGLUTARATE_DEHYDROGENASE,_MITOCHONDRIAL PTHR43716.orig.30.pir ENERGY_CONSERVATION ATP DLDH PTHR43716.SF1.mod D-2-HYDROXYGLUTARATE_DEHYDROGENASE,_MITOCHONDRIAL PTHR43716.SF1.pir ENERGY_CONSERVATION ATP CysJ-fused_HydA PTHR19384.mag.mod NITRIC_OXIDE_SYNTHASE-RELATED PTHR19384.orig.30.pir ENERGY_CONSERVATION ATP CysJ-fused_HydA PTHR19384.SF109.mod SULFITE_REDUCTASE_[NADPH]_FLAVOPROTEIN_COMPONENT PTHR19384.SF109.pir ENERGY_CONSERVATION ATP CysJ-fused_HydA PTHR19384.SF17.mod NADPH--CYTOCHROME_P450_REDUCTASE PTHR19384.SF17.pir ENERGY_CONSERVATION ATP PFL PTHR30191.mag.mod FORMATE_ACETYLTRANSFERASE PTHR30191.orig.30.pir ENERGY_CONSERVATION ATP PFL PTHR30191.SF0.mod FORMATE_ACETYLTRANSFERASE_1 PTHR30191.SF0.pir ENERGY_CONSERVATION ATP ACS PTHR42793.mag.mod COA_BINDING_DOMAIN_CONTAINING_PROTEIN PTHR42793.orig.30.pir ENERGY_CONSERVATION ATP ACS PTHR42793.SF1.mod PEPTIDYL-LYSINE_N-ACETYLTRANSFERASE_PATZ PTHR42793.SF1.pir ENERGY_CONSERVATION ATP ACS PTHR43334.mag.mod ACETATE--COA_LIGASE_[ADP-FORMING] PTHR43334.orig.30.pir ENERGY_CONSERVATION ATP ACS PTHR43334.SF1.mod ACETATE--COA_LIGASE_[ADP-FORMING] PTHR43334.SF1.pir ENERGY_CONSERVATION ATP MM-CoA-epimerase PTHR43048.mag.mod METHYLMALONYL-COA_EPIMERASE PTHR43048.orig.30.pir ENERGY_CONSERVATION ATP MM-CoA-epimerase PTHR43048.SF3.mod METHYLMALONYL-COA_EPIMERASE,_MITOCHONDRIAL PTHR43048.SF3.pir ENERGY_CONSERVATION ATP MM-CoA-mutase PTHR48101.SF4.mod METHYLMALONYL-COA_MUTASE,_MITOCHONDRIAL PTHR48101.SF4.pir ENERGY_CONSERVATION ATP MM-CoA-mutase PTHR48101.mag.mod METHYLMALONYL-COA_MUTASE,_MITOCHONDRIAL-RELATED PTHR48101.orig.30.pir ENERGY_CONSERVATION ATP MMSA-dehydrogenase PTHR43866.mag.mod MALONATE-SEMIALDEHYDE_DEHYDROGENASE PTHR43866.orig.30.pir ENERGY_CONSERVATION ATP MMSA-dehydrogenase PTHR43866.SF3.mod METHYLMALONATE-SEMIALDEHYDE_DEHYDROGENASE_[ACYLATING],_MITOCHONDRIAL PTHR43866.SF3.pir ENERGY_CONSERVATION ATP PCCa PTHR18866.mag.mod CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA_CARBOXYLASE PTHR18866.orig.30.pir ENERGY_CONSERVATION ATP PCCa PTHR18866.SF33.mod METHYLCROTONOYL-COA_CARBOXYLASE_SUBUNIT_ALPHA,_MITOCHONDRIAL-RELATED PTHR18866.SF33.pir ENERGY_CONSERVATION ATP PCCb PTHR43842.mag.mod PROPIONYL-COA_CARBOXYLASE_BETA_CHAIN PTHR43842.orig.30.pir ENERGY_CONSERVATION ATP PCCb PTHR43842.SF2.mod PROPIONYL-COA_CARBOXYLASE_BETA_CHAIN-RELATED PTHR43842.SF2.pir ENERGY_CONSERVATION ATP PCCb PTHR45728.SF3.mod ACETYL-COA_CARBOXYLASE PTHR45728.SF3.pir ENERGY_CONSERVATION ATP PCCb PTHR45728.mag.mod ACETYL-COA_CARBOXYLASE,_ISOFORM_A PTHR45728.orig.30.pir ENERGY_CONSERVATION ATP 3HB-dehydrogenase PTHR43060.mag.mod 3-HYDROXYISOBUTYRATE_DEHYDROGENASE-LIKE_1,_MITOCHONDRIAL-RELATED PTHR43060.orig.30.pir ENERGY_CONSERVATION ATP 3HB-dehydrogenase PTHR43060.SF15.mod 3-HYDROXYISOBUTYRATE_DEHYDROGENASE-LIKE_1,_MITOCHONDRIAL-RELATED PTHR43060.SF15.pir
NOTE that I've included for every gene the family and the subfamily identifier. So, which of these are in our genome?
cat ergo_vs_panther17.filt.ext.domtblout \
| body rg -f <(cut -f 6 families_of_interest.ATP.upd.list) \
| body sort -k28,28 \
> ergo_vs_panther17.ATP.ext.domtblout
rg is a modern unix tool that is very similar to the classic grep (it is literally called ripgrep) but its a lot faster, particularly with the -f option.
We now get the following file
TargetName TargetAcc TargetLen QueryName QueryAcc QueryLen seq-E-value seq-Score seq-Bias dom-No dom-Count dom-c-Evalue dom-i-Evalue dom-Score dom-Bias hmm-From hmm-To ali-From ali-To env-From env-To mean-PP DescriptionOfTarget qcovhsp tcovhsp qcovs tcovs annotation PTHR43726.orig.30.pir - 384 FUN_005298-T1 - 390 7.1e-100 337.2 0.0 1 1 8.8e-104 8.9e-100 336.9 0.0 45 380 18 380 5 383 0.94 - 0.93 0.88 0.93 0.88 3-METHYLORNITHINE_SYNTHASE PTHR43334.orig.30.pir - 705 FUN_004883-T1 - 761 1.1e-247 826.9 0.0 1 1 1.3e-251 1.4e-247 826.6 0.0 4 702 31 733 29 736 0.98 - 0.92 0.99 0.92 0.99 ACETATE--COA_LIGASE_[ADP-FORMING] PTHR43334.orig.30.pir - 705 FUN_004897-T1 - 647 1.4e-224 750.4 0.0 1 1 1.7e-228 1.8e-224 750.1 0.0 1 630 12 643 12 646 0.98 - 0.98 0.89 0.98 0.89 ACETATE--COA_LIGASE_[ADP-FORMING] PTHR43583.SF2.pir - 498 FUN_005007-T1 - 570 6e-189 631.4 0.0 1 1 5.7e-193 7.3e-189 631.1 0.0 19 498 58 570 31 570 0.97 - 0.90 0.96 0.90 0.96 BIOTIN_AND_THIAMIN_SYNTHESIS_ASSOCIATED_DOMAIN_CONTAINING_PROTEIN PTHR43583.SF2.pir - 498 FUN_005031-T1 - 570 7.6e-189 631.1 0.0 1 1 7.2e-193 9.3e-189 630.8 0.0 19 498 58 570 31 570 0.97 - 0.90 0.96 0.90 0.96 BIOTIN_AND_THIAMIN_SYNTHESIS_ASSOCIATED_DOMAIN_CONTAINING_PROTEIN PTHR11615.SF345.pir - 585 FUN_003250-T1 - 583 5.5e-167 559.9 0.2 1 1 1.1e-170 6.3e-167 559.7 0.2 6 581 5 579 1 582 0.94 - 0.99 0.98 0.99 0.98 CATALYTIC_SUBUNIT_OF_IRON-ONLY_HYDROGENASE-RELATED PTHR11615.SF345.pir - 585 FUN_003742-T1 - 461 3.9e-127 428.3 1.4 1 1 5.8e-131 6.9e-127 427.5 1.4 139 580 31 460 4 461 0.92 - 0.93 0.76 0.93 0.76 CATALYTIC_SUBUNIT_OF_IRON-ONLY_HYDROGENASE-RELATED PTHR42793.orig.30.pir - 472 FUN_000469-T1 - 843 1.5e-104 353.0 0.0 1 1 5.9e-109 1.7e-104 352.9 0.0 5 460 352 842 146 843 0.93 - 0.58 0.97 0.58 0.97 COA_BINDING_DOMAIN_CONTAINING_PROTEIN PTHR23426.SF65.pir - 153 FUN_000689-T1 - 116 1.5e-13 54.3 0.0 1 1 1.7e-17 1.7e-13 54.1 0.0 57 142 28 109 14 115 0.87 - 0.71 0.56 0.71 0.56 FERREDOXIN_1-RELATED PTHR23426.SF65.pir - 153 FUN_001937-T1 - 106 2.1e-13 53.8 0.1 1 1 1.9e-17 2.4e-13 53.6 0.1 46 139 8 99 3 105 0.81 - 0.87 0.61 0.87 0.61 FERREDOXIN_1-RELATED PTHR30191.SF0.pir - 749 FUN_003588-T1 - 742 0.0 1182.9 0.1 1 1 0.0 0.0 1182.7 0.1 20 748 4 741 1 742 0.98 - 0.99 0.97 0.99 0.97 FORMATE_ACETYLTRANSFERASE_1 PTHR30191.SF0.pir - 749 FUN_004683-T1 - 779 0.0 1200.2 0.0 1 1 0.0 0.0 1199.9 0.0 15 748 36 778 26 779 0.98 - 0.95 0.98 0.95 0.98 FORMATE_ACETYLTRANSFERASE_1 PTHR30191.SF0.pir - 749 FUN_004725-T1 - 744 0.0 1199.6 0.0 1 1 0.0 0.0 1199.4 0.0 21 748 7 743 1 744 0.98 - 0.99 0.97 0.99 0.97 FORMATE_ACETYLTRANSFERASE_1 PTHR30191.SF0.pir - 749 FUN_004737-T1 - 744 0.0 1199.6 0.0 1 1 0.0 0.0 1199.4 0.0 21 748 7 743 1 744 0.98 - 0.99 0.97 0.99 0.97 FORMATE_ACETYLTRANSFERASE_1 PTHR30191.SF0.pir - 749 FUN_006165-T1 - 744 0.0 1196.1 0.0 1 1 0.0 0.0 1195.9 0.0 22 748 8 743 3 744 0.98 - 0.99 0.97 0.99 0.97 FORMATE_ACETYLTRANSFERASE_1 PTHR11615.SF304.pir - 431 FUN_004893-T1 - 1202 5.6e-80 272.2 0.0 1 2 0.0045 19.0 6.9 0.8 44 65 219 257 147 271 0.7 - 0.03 0.05 0.63 0.89 IRON_HYDROGENASE,_PUTATIVE-RELATED PTHR11615.SF304.pir - 431 FUN_005208-T1 - 1444 5.2e-84 285.5 0.0 1 4 1.1e-06 0.0045 18.8 5.8 44 75 288 340 187 347 0.72 - 0.04 0.07 0.38 0.86 IRON_HYDROGENASE,_PUTATIVE-RELATED PTHR11780.SF10.pir - 449 FUN_001132-T1 - 414 4.3e-83 282.2 0.0 1 2 1.8e-53 3.6e-49 170.4 0.0 67 210 2 180 1 194 0.97 - 0.43 0.32 0.74 0.59 NADH_DEHYDROGENASE_[UBIQUINONE]_FLAVOPROTEIN_1,_MITOCHONDRIAL PTHR10371.orig.30.pir - 230 FUN_002223-T1 - 208 7.2e-51 175.7 0.0 1 1 2.6e-55 7.4e-51 175.7 0.0 29 183 8 166 2 208 0.88 - 0.76 0.67 0.76 0.67 NADH_DEHYDROGENASE__UBIQUINONE__FLAVOPROTEIN_2,_MITOCHONDRIAL PTHR11780.orig.30.pir - 449 FUN_000599-T1 - 466 8.9e-152 508.6 0.0 1 1 7.2e-156 1.1e-151 508.2 0.0 14 430 38 456 29 464 0.95 - 0.90 0.93 0.90 0.93 NADH-UBIQUINONE_OXIDOREDUCTASE_FLAVOPROTEIN_1__NDUFV1 PTHR23406.SF32.pir - 596 FUN_001722-T1 - 585 2.8e-186 623.3 0.0 1 1 6.5e-190 3.4e-186 623.1 0.0 43 591 20 585 2 585 0.93 - 0.97 0.92 0.97 0.92 NADP-DEPENDENT_MALIC_ENZYME PTHR23406.SF32.pir - 596 FUN_003026-T1 - 563 4.2e-195 652.5 0.0 1 1 9.7e-199 5.1e-195 652.2 0.0 39 593 11 552 2 555 0.96 - 0.96 0.93 0.96 0.93 NADP-DEPENDENT_MALIC_ENZYME PTHR23406.SF32.pir - 596 FUN_003030-T1 - 563 4.2e-195 652.5 0.0 1 1 9.7e-199 5.1e-195 652.2 0.0 39 593 11 552 2 555 0.96 - 0.96 0.93 0.96 0.93 NADP-DEPENDENT_MALIC_ENZYME PTHR32154.SF0.pir - 1159 FUN_000496-T1 - 1228 0.0 1568.0 0.0 1 1 0.0 0.0 1567.6 0.0 3 1156 51 1226 48 1227 0.98 - 0.96 1.00 0.96 1.00 PYRUVATE-FLAVODOXIN_OXIDOREDUCTASE-RELATED PTHR32154.SF0.pir - 1159 FUN_000974-T1 - 1261 0.0 1402.3 0.0 1 1 0.0 0.0 1402.0 0.0 5 1154 81 1256 78 1261 0.97 - 0.93 0.99 0.93 0.99 PYRUVATE-FLAVODOXIN_OXIDOREDUCTASE-RELATED PTHR32154.SF0.pir - 1159 FUN_003906-T1 - 1427 0.0 1268.7 0.0 1 1 0.0 0.0 1264.6 0.0 5 1156 101 1383 98 1394 0.95 - 0.90 0.99 0.90 0.99 PYRUVATE-FLAVODOXIN_OXIDOREDUCTASE-RELATED PTHR32154.SF0.pir - 1159 FUN_004094-T1 - 1404 0.0 1481.8 0.0 1 1 0.0 0.0 1481.4 0.0 4 1154 3 1223 1 1228 0.96 - 0.87 0.99 0.87 0.99 PYRUVATE-FLAVODOXIN_OXIDOREDUCTASE-RELATED PTHR11117.SF2.pir - 320 FUN_001614-T1 - 326 6.7e-140 468.5 4.9 1 1 1.1e-143 7.9e-140 468.2 4.9 21 318 25 319 6 321 0.96 - 0.90 0.93 0.90 0.93 SUCCINATE--COA_LIGASE_[ADP/GDP-FORMING]_SUBUNIT_ALPHA,_MITOCHONDRIAL PTHR11815.orig.30.pir - 402 FUN_002952-T1 - 408 3.8e-159 532.8 0.0 1 1 3.9e-163 4.6e-159 532.5 0.0 5 399 7 405 4 408 0.98 - 0.98 0.98 0.98 0.98 SUCCINYL-COA_SYNTHETASE_BETA_CHAIN PTHR42714.SF6.pir - 467 FUN_004742-T1 - 491 6.2e-29 104.5 0.0 1 1 5e-31 4.2e-27 98.5 0.0 70 441 18 413 15 434 0.71 - 0.81 0.80 0.81 0.80 TRANSLATION_INITIATION_FACTOR_IF-2
To verify that each of these proteins are truly orthologs of the PANTHER families, we'd have to make trees, but this is a good starting point.
NOTE that we purposefully started by comparing our proteins to the entire PANTHER HMM-profile database, rather than starting out from a selection of HMM-profiles of gene families that we know we are interested in. This prevents false positive associations between our protein and and HMM profile:
Let's say that our genome doesn't have an ortholog of PANTHER family A, but it does have a distant paralog of that family (represented in the PANTHER database by family B). We are interested in A, but not in B. If we search with PANTHER family A, but not with family B, we may get a significant hit against family A, even though its not a true ortholog. If we were to include family B in our search as well, then we'd get significant hits against family A and B, but the score against B would be much better. It is thus clear that our protein is not a true ortholog of family A.
Premade categories of PANTHER families of interest
Mitochondria related
Energy conservation
ENERGY_CONSERVATION ATP ME PTHR23406.mag.mod MALIC_ENZYME-RELATED PTHR23406.orig.30.pir ENERGY_CONSERVATION ATP ME PTHR23406.SF32.mod NADP-DEPENDENT_MALIC_ENZYME PTHR23406.SF32.pir ENERGY_CONSERVATION ATP PNO/PFO PTHR32154.mag.mod PYRUVATE-FLAVODOXIN_OXIDOREDUCTASE-RELATED PTHR32154.orig.30.pir ENERGY_CONSERVATION ATP PNO/PFO PTHR32154.SF0.mod PYRUVATE-FLAVODOXIN_OXIDOREDUCTASE-RELATED PTHR32154.SF0.pir ENERGY_CONSERVATION ATP Adrenodoxin/Ferredoxin_Yah1 PTHR23426.mag.mod FERREDOXIN/ADRENODOXIN PTHR23426.orig.30.pir ENERGY_CONSERVATION ATP Adrenodoxin/Ferredoxin_Yah1 PTHR23426.SF65.mod FERREDOXIN_1-RELATED PTHR23426.SF65.pir ENERGY_CONSERVATION ATP Adrenodoxin/Ferredoxin_Yah1 PTHR23426.SF63.mod TRANSFER_PROTEIN,_PUTATIVE-RELATED PTHR23426.SF63.pir ENERGY_CONSERVATION ATP FdxR/Arh1 PTHR11938.mag.mod FAD_NADPH_DEHYDROGENASE/OXIDOREDUCTASE PTHR11938.orig.30.pir ENERGY_CONSERVATION ATP FdxR/Arh1 PTHR11938.SF91.mod NADPH:ADRENODOXIN_OXIDOREDUCTASE,_MITOCHONDRIAL PTHR11938.SF91.pir ENERGY_CONSERVATION ATP HydA PTHR11615.mag.mod NITRATE,_FORMATE,_IRON_DEHYDROGENASE PTHR11615.orig.30.pir ENERGY_CONSERVATION ATP HydA-1 PTHR11615.SF345.mod CATALYTIC_SUBUNIT_OF_IRON-ONLY_HYDROGENASE-RELATED PTHR11615.SF345.pir ENERGY_CONSERVATION ATP HydA-4 PTHR11615.SF304.mod IRON_HYDROGENASE,_PUTATIVE-RELATED PTHR11615.SF304.pir ENERGY_CONSERVATION ATP HydE PTHR43726.mag.mod 3-METHYLORNITHINE_SYNTHASE PTHR43726.orig.30.pir ENERGY_CONSERVATION ATP HydE PTHR43726.SF1.mod [FEFE]_HYDROGENASE_MATURASE_SUBUNIT_HYDE PTHR43726.SF1.pir ENERGY_CONSERVATION ATP HydF PTHR42714.mag.mod TRNA_MODIFICATION_GTPASE_GTPBP3 PTHR42714.orig.30.pir ENERGY_CONSERVATION ATP HydF PTHR42714.SF6.mod TRANSLATION_INITIATION_FACTOR_IF-2 PTHR42714.SF6.pir ENERGY_CONSERVATION ATP HydG PTHR43583.mag.mod 2-IMINOACETATE_SYNTHASE PTHR43583.orig.30.pir ENERGY_CONSERVATION ATP HydG PTHR43583.SF2.mod BIOTIN_AND_THIAMIN_SYNTHESIS_ASSOCIATED_DOMAIN_CONTAINING_PROTEIN PTHR43583.SF2.pir ENERGY_CONSERVATION ATP NuoF/Complex_I_51kDa PTHR11780.mag.mod NADH-UBIQUINONE_OXIDOREDUCTASE_FLAVOPROTEIN_1_NDUFV1 PTHR11780.orig.30.pir ENERGY_CONSERVATION ATP NuoF/Complex_I_51kDa PTHR11780.SF10.mod NADH_DEHYDROGENASE_[UBIQUINONE]_FLAVOPROTEIN_1,_MITOCHONDRIAL PTHR11780.SF10.pir ENERGY_CONSERVATION ATP NuoE/Complex_I_24kDa PTHR10371.mag.mod NADH_DEHYDROGENASE_UBIQUINONE_FLAVOPROTEIN_2,_MITOCHONDRIAL PTHR10371.orig.30.pir ENERGY_CONSERVATION ATP NuoE/Complex_I_24kDa PTHR10371.SF3.mod NADH_DEHYDROGENASE_[UBIQUINONE]_FLAVOPROTEIN_2,_MITOCHONDRIAL PTHR10371.SF3.pir ENERGY_CONSERVATION ATP ASCT-1A PTHR13707.mag.mod KETOACID-COENZYME_A_TRANSFERASE PTHR13707.orig.30.pir ENERGY_CONSERVATION ATP ASCT-1A PTHR13707.SF23.mod SUCCINYL-COA:3-KETOACID-COENZYME_A_TRANSFERASE PTHR13707.SF23.30.pir ENERGY_CONSERVATION ATP ASCT-1B PTHR21432.mag.mod ACETYL-COA_HYDROLASE-RELATED PTHR21432.orig.30.pir ENERGY_CONSERVATION ATP ASCT-1B PTHR21432.SF20.mod ACETYL-COA_DEACYLASE PTHR21432.SF20.pir ENERGY_CONSERVATION ATP ASCT-1C PTHR43609.mag.mod ACETYL-COA_HYDROLASE PTHR43609.orig.30.pir ENERGY_CONSERVATION ATP ASCT-1C PTHR43609.SF1.mod ACETYL-COA_HYDROLASE PTHR43609.SF1.pir ENERGY_CONSERVATION ATP SCSa/STKa PTHR11117.mag.mod SUCCINYL-COA_LIGASE_SUBUNIT_ALPHA PTHR11117.orig.30.pir ENERGY_CONSERVATION ATP SCSa/STKa PTHR11117.SF2.mod SUCCINATE--COA_LIGASE_[ADP/GDP-FORMING]_SUBUNIT_ALPHA,_MITOCHONDRIAL PTHR11117.SF2.pir ENERGY_CONSERVATION ATP SCSb/STKb PTHR11815.mag.mod SUCCINYL-COA_SYNTHETASE_BETA_CHAIN PTHR11815.orig.30.pir ENERGY_CONSERVATION ATP SCSb/STKb PTHR11815.SF10.mod SUCCINATE--COA_LIGASE_[GDP-FORMING]_SUBUNIT_BETA,_MITOCHONDRIAL PTHR11815.SF10.pir ENERGY_CONSERVATION ATP DLDH PTHR43716.mag.mod D-2-HYDROXYGLUTARATE_DEHYDROGENASE,_MITOCHONDRIAL PTHR43716.orig.30.pir ENERGY_CONSERVATION ATP DLDH PTHR43716.SF1.mod D-2-HYDROXYGLUTARATE_DEHYDROGENASE,_MITOCHONDRIAL PTHR43716.SF1.pir ENERGY_CONSERVATION ATP CysJ-fused_HydA PTHR19384.mag.mod NITRIC_OXIDE_SYNTHASE-RELATED PTHR19384.orig.30.pir ENERGY_CONSERVATION ATP CysJ-fused_HydA PTHR19384.SF109.mod SULFITE_REDUCTASE_[NADPH]_FLAVOPROTEIN_COMPONENT PTHR19384.SF109.pir ENERGY_CONSERVATION ATP CysJ-fused_HydA PTHR19384.SF17.mod NADPH--CYTOCHROME_P450_REDUCTASE PTHR19384.SF17.pir ENERGY_CONSERVATION ATP PFL PTHR30191.mag.mod FORMATE_ACETYLTRANSFERASE PTHR30191.orig.30.pir ENERGY_CONSERVATION ATP PFL PTHR30191.SF0.mod FORMATE_ACETYLTRANSFERASE_1 PTHR30191.SF0.pir ENERGY_CONSERVATION ATP ACS PTHR42793.mag.mod COA_BINDING_DOMAIN_CONTAINING_PROTEIN PTHR42793.orig.30.pir ENERGY_CONSERVATION ATP ACS PTHR42793.SF1.mod PEPTIDYL-LYSINE_N-ACETYLTRANSFERASE_PATZ PTHR42793.SF1.pir ENERGY_CONSERVATION ATP ACS PTHR43334.mag.mod ACETATE--COA_LIGASE_[ADP-FORMING] PTHR43334.orig.30.pir ENERGY_CONSERVATION ATP ACS PTHR43334.SF1.mod ACETATE--COA_LIGASE_[ADP-FORMING] PTHR43334.SF1.pir ENERGY_CONSERVATION ATP MM-CoA-epimerase PTHR43048.mag.mod METHYLMALONYL-COA_EPIMERASE PTHR43048.orig.30.pir ENERGY_CONSERVATION ATP MM-CoA-epimerase PTHR43048.SF3.mod METHYLMALONYL-COA_EPIMERASE,_MITOCHONDRIAL PTHR43048.SF3.pir ENERGY_CONSERVATION ATP MM-CoA-mutase PTHR48101.SF4.mod METHYLMALONYL-COA_MUTASE,_MITOCHONDRIAL PTHR48101.SF4.pir ENERGY_CONSERVATION ATP MM-CoA-mutase PTHR48101.mag.mod METHYLMALONYL-COA_MUTASE,_MITOCHONDRIAL-RELATED PTHR48101.orig.30.pir ENERGY_CONSERVATION ATP MMSA-dehydrogenase PTHR43866.mag.mod MALONATE-SEMIALDEHYDE_DEHYDROGENASE PTHR43866.orig.30.pir ENERGY_CONSERVATION ATP MMSA-dehydrogenase PTHR43866.SF3.mod METHYLMALONATE-SEMIALDEHYDE_DEHYDROGENASE_[ACYLATING],_MITOCHONDRIAL PTHR43866.SF3.pir ENERGY_CONSERVATION ATP PCCa PTHR18866.mag.mod CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA_CARBOXYLASE PTHR18866.orig.30.pir ENERGY_CONSERVATION ATP PCCa PTHR18866.SF33.mod METHYLCROTONOYL-COA_CARBOXYLASE_SUBUNIT_ALPHA,_MITOCHONDRIAL-RELATED PTHR18866.SF33.pir ENERGY_CONSERVATION ATP PCCb PTHR43842.mag.mod PROPIONYL-COA_CARBOXYLASE_BETA_CHAIN PTHR43842.orig.30.pir ENERGY_CONSERVATION ATP PCCb PTHR43842.SF2.mod PROPIONYL-COA_CARBOXYLASE_BETA_CHAIN-RELATED PTHR43842.SF2.pir ENERGY_CONSERVATION ATP PCCb PTHR45728.SF3.mod ACETYL-COA_CARBOXYLASE PTHR45728.SF3.pir ENERGY_CONSERVATION ATP PCCb PTHR45728.mag.mod ACETYL-COA_CARBOXYLASE,_ISOFORM_A PTHR45728.orig.30.pir ENERGY_CONSERVATION ATP 3HB-dehydrogenase PTHR43060.mag.mod 3-HYDROXYISOBUTYRATE_DEHYDROGENASE-LIKE_1,_MITOCHONDRIAL-RELATED PTHR43060.orig.30.pir ENERGY_CONSERVATION ATP 3HB-dehydrogenase PTHR43060.SF15.mod 3-HYDROXYISOBUTYRATE_DEHYDROGENASE-LIKE_1,_MITOCHONDRIAL-RELATED PTHR43060.SF15.pir
Iron-Sulfur cluster biosynthesis
IRON_SULFUR_CLUSTER_ASSEMBLY FeS Frataxin/FXN PTHR16821.mag.mod FRATAXIN PTHR16821.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Frataxin/FXN PTHR16821.SF2.mod FRATAXIN,_MITOCHONDRIAL PTHR16821.SF2.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Adrenodoxin/Ferredoxin_Yah1 PTHR23426.mag.mod FERREDOXIN/ADRENODOXIN PTHR23426.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Adrenodoxin/Ferredoxin_Yah1 PTHR23426.SF65.mod FERREDOXIN_1-RELATED PTHR23426.SF65.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Adrenodoxin/Ferredoxin_Yah1 PTHR23426.SF63.mod TRANSFER PROTEIN,_PUTATIVE-RELATED PTHR23426.SF63.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS FdxR/Arh1 PTHR11938.mag.mod FAD_NADPH_DEHYDROGENASE/OXIDOREDUCTASE PTHR11938.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS FdxR/Arh1 PTHR11938.SF91.mod NADPH:ADRENODOXIN_OXIDOREDUCTASE,_MITOCHONDRIAL PTHR11938.SF91.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS IscS/Nfs1 PTHR11601.mag.mod CYSTEINE_DESULFURYLASE_FAMILY_MEMBER PTHR11601.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS IscS/Nfs1 PTHR11601.SF34.mod CYSTEINE_DESULFURASE,_MITOCHONDRIAL PTHR11601.SF34.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Isd11 PTHR13166.mag.mod PROTEIN_C6ORF149 PTHR13166.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Isd11 PTHR13166.SF7.mod LYR_MOTIF-CONTAINING_PROTEIN_4 PTHR13166.SF7.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS IscU/NifU PTHR10093.mag.mod IRON-SULFUR_CLUSTER_ASSEMBLY_ENZYME__NIFU_HOMOLOG PTHR10093.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS IscU/NifU PTHR10093.SF8.mod NIFU_N_DOMAIN-CONTAINING_PROTEIN PTHR10093.SF8.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS mtHsp70/SSQ1 PTHR19375.mag.mod HEAT_SHOCK_PROTEIN_70KDA PTHR19375.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS mtHsp70/SSQ1 PTHR19375.SF184.mod STRESS-70_PROTEIN,_MITOCHONDRIAL PTHR19375.SF184.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS mtHsp70/SSQ1 PTHR19375.SF197.mod IRON-SULFUR_CLUSTER_BIOGENESIS_CHAPERONE,_MITOCHONDRIAL PTHR19375.SF197.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS mtHsp70/SSQ1 PTHR19375.SF510.mod HEAT_SHOCK_70_KDA_PROTEIN,_MITOCHONDRIAL PTHR19375.SF510.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS GrpE1/Mge1 PTHR21237.mag.mod GRPE_PROTEIN PTHR21237.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS GrpE1/Mge1 PTHR21237.SF23.mod GRPE_PROTEIN_HOMOLOG,_MITOCHONDRIAL PTHR21237.SF23.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Glrx5 PTHR10293.mag.mod GLUTAREDOXIN_FAMILY_MEMBER PTHR10293.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Glrx5 PTHR10293.SF16.mod GLUTAREDOXIN-RELATED_PROTEIN_5,_MITOCHONDRIAL PTHR10293.SF16.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Glrx5 PTHR10293.SF72.mod MONOTHIOL_GLUTAREDOXIN-S14,_CHLOROPLASTIC PTHR10293.SF72.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS IscA1 PTHR10072.mag.mod IRON-SULFUR_CLUSTER_ASSEMBLY_PROTEIN PTHR10072.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS IscA1 PTHR10072.SF41.mod IRON-SULFUR_CLUSTER_ASSEMBLY_1_HOMOLOG,_MITOCHONDRIAL PTHR10072.SF41.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS IscA2 PTHR43011.mag.mod IRON-SULFUR_CLUSTER_ASSEMBLY_2_HOMOLOG,_MITOCHONDRIAL PTHR43011.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS IscA2 PTHR43011.SF1.mod IRON-SULFUR_CLUSTER_ASSEMBLY_2_HOMOLOG,_MITOCHONDRIAL PTHR43011.SF1.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Nfu1 PTHR11178.mag.mod IRON-SULFUR_CLUSTER_SCAFFOLD_PROTEIN_NFU-RELATED PTHR11178.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Nfu1 PTHR11178.SF1.mod NFU1_IRON-SULFUR_CLUSTER_SCAFFOLD_HOMOLOG,_MITOCHONDRIAL PTHR11178.SF1.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS IND1 PTHR42961.mag.mod IRON-SULFUR_PROTEIN_NUBPL PTHR42961.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS IND1 PTHR42961.SF2.mod IRON-SULFUR_PROTEIN_NUBPL PTHR42961.SF2.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS BolA1 PTHR46230.mag.mod FAMILY_NOT_NAMED PTHR46230.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS BolA1 PTHR46230.SF4.mod BOLA-LIKE_PROTEIN_1 PTHR46230.SF4.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Jac1/HscB/Hsc20 PTHR14021.mag.mod IRON-SULFUR_CLUSTER_CO-CHAPERONE_PROTEIN_HSCB PTHR14021.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Jac1/HscB/Hsc20 PTHR14021.SF15.mod IRON-SULFUR_CLUSTER_CO-CHAPERONE_PROTEIN_HSCB PTHR14021.SF15.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Atm1 PTHR24221.mag.mod ATP-BINDING_CASSETTE_SUB-FAMILY_B PTHR24221.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Atm1 PTHR24221.SF402.mod IRON-SULFUR_CLUSTERS_TRANSPORTER_ABCB7,_MITOCHONDRIAL PTHR24221.SF402.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Xxx1 PTHR24089.mag.mod SOLUTE_CARRIER_FAMILY_25 PTHR24089.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Xxx1 PTHR24089.SF442.mod MITOCHONDRIAL_SUBSTRATE_CARRIER_FAMILY_PROTEIN_A PTHR24089.SF442.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Xxx2 PTHR43687.mag.mod ADENYLYLSULFATE_REDUCTASE,_BETA_SUBUNIT_ PTHR43687.SF1.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Xxx2 PTHR43687.SF1.mod L-ASPARTATE_SEMIALDEHYDE_SULFURTRANSFERASE_IRON-SULFUR_SUBUNIT PTHR43687.SF1.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Erv1 PTHR12645.mag.mod ALR/ERV PTHR12645.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS Erv1 PTHR12645.SF0.mod FAD-LINKED_SULFHYDRYL_OXIDASE_ALR PTHR12645.SF0.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS SufCB PTHR30508.mag.mod FES_CLUSTER_ASSEMBLY_PROTEIN_SUF PTHR30508.orig.30.pir IRON_SULFUR_CLUSTER_ASSEMBLY FeS SufCB PTHR30508.SF1.mod UPF0051_PROTEIN_ABCI8,_CHLOROPLASTIC-RELATED PTHR30508.SF1.pir
Electron Transfer
Electron_transfer CAT_SHORT_NAME Alternative_oxidase PTHR31803.mag.mod ALTERNATIVE_OXIDASE PTHR31803.orig.30.pir Electron_transfer CAT_SHORT_NAME Alternative_oxidase PTHR31803.SF3.mod ALTERNATIVE_OXIDASE PTHR31803.SF3.pir Electron_transfer CAT_SHORT_NAME ETF-alpha PTHR43153.mag.mod ELECTRON_TRANSFER_FLAVOPROTEIN_ALPHA PTHR43153.orig.30.pir Electron_transfer CAT_SHORT_NAME ETF-alpha PTHR43153.SF1.mod ELECTRON_TRANSFER_FLAVOPROTEIN_SUBUNIT_ALPHA,_MITOCHONDRIAL PTHR43153.SF1.pir Electron_transfer CAT_SHORT_NAME ETF-beta PTHR21294.mag.mod ELECTRON_TRANSFER_FLAVOPROTEIN_BETA-SUBUNIT PTHR21294.orig.30.pir Electron_transfer CAT_SHORT_NAME ETF-beta PTHR21294.SF8.mod ELECTRON_TRANSFER_FLAVOPROTEIN_SUBUNIT_BETA PTHR21294.SF8.pir Electron_transfer CAT_SHORT_NAME ETF-ubiquinone_oxidoreductase_1 PTHR10617.mag.mod ELECTRON_TRANSFER_FLAVOPROTEIN-UBIQUINONE_OXIDOREDUCTASE PTHR10617.orig.30.pir Electron_transfer CAT_SHORT_NAME ETF-ubiquinone_oxidoreductase_1 PTHR10617.SF107.mod ELECTRON_TRANSFER_FLAVOPROTEIN-UBIQUINONE_OXIDOREDUCTASE,_MITOCHONDRIAL PTHR10617.SF107.pir Electron_transfer CAT_SHORT_NAME ETF-ubiquinone_oxidoreductase_2 PTHR10617.mag.mod ELECTRON_TRANSFER_FLAVOPROTEIN-UBIQUINONE_OXIDOREDUCTASE PTHR10617.orig.30.pir Electron_transfer CAT_SHORT_NAME ETF-ubiquinone_oxidoreductase_2 PTHR10617.SF107.mod ELECTRON_TRANSFER_FLAVOPROTEIN-UBIQUINONE_OXIDOREDUCTASE,_MITOCHONDRIAL PTHR10617.SF107.pir Electron_transfer CAT_SHORT_NAME Glycerol-3-phosphate_DH PTHR11985.mag.mod GLYCEROL-3-PHOSPHATE_DEHYDROGENASE PTHR11985.orig.30.pir Electron_transfer CAT_SHORT_NAME Glycerol-3-phosphate_DH PTHR11985.SF15.mod GLYCEROL-3-PHOSPHATE_DEHYDROGENASE,_MITOCHONDRIAL PTHR11985.SF15.pir Electron_transfer CAT_SHORT_NAME cytosolic_flavoprotein_A PTHR32145.mag.mod DIFLAVIN_FLAVOPROTEIN_A_2-RELATED PTHR32145.orig.30.pir Electron_transfer CAT_SHORT_NAME cytosolic_flavoprotein_A PTHR32145.SF11.mod DIFLAVIN_FLAVOPROTEIN_A_2-RELATED PTHR32145.SF11.pir
Amino acid metabolism
AMINO_ACID_METABOLISM AA GCS-L PTHR22912.mag.mod DISULFIDE_OXIDOREDUCTASE PTHR22912.orig.30.pir AMINO_ACID_METABOLISM AA GCS-L PTHR22912.SF151.mod DIHYDROLIPOYL_DEHYDROGENASE,_MITOCHONDRIAL PTHR22912.SF151.pir AMINO_ACID_METABOLISM AA GCS-L PTHR22912.SF211.mod DIHYDROLIPOYL_DEHYDROGENASE_2,_MITOCHONDRIAL PTHR22912.SF211.pir AMINO_ACID_METABOLISM AA GCS-L PTHR22912.SF223.mod DIHYDROLIPOYL_DEHYDROGENASE_1,_MITOCHONDRIAL PTHR22912.SF223.pir AMINO_ACID_METABOLISM AA GCS-H PTHR11715.mag.mod GLYCINE_CLEAVAGE_SYSTEM_H_PROTEIN PTHR11715.orig.30.pir AMINO_ACID_METABOLISM AA GCS-H PTHR11715.SF3.mod GLYCINE_CLEAVAGE_SYSTEM_H_PROTEIN,_MITOCHONDRIAL PTHR11715.SF3.pir AMINO_ACID_METABOLISM AA GCS-P1 PTHR42806.mag.mod GLYCINE_CLEAVAGE_SYSTEM_P-PROTEIN PTHR42806.orig.30.pir AMINO_ACID_METABOLISM AA GCS-P1 PTHR42806.SF1.mod GLYCINE_DEHYDROGENASE_(DECARBOXYLATING) PTHR42806.SF1.pir AMINO_ACID_METABOLISM AA GCS-P2 PTHR11773.mag.mod GLYCINE_DEHYDROGENASE,_DECARBOXYLATING PTHR11773.orig.30.pir AMINO_ACID_METABOLISM AA GCS-P2 PTHR11773.SF1.mod GLYCINE_DEHYDROGENASE_(DECARBOXYLATING),_MITOCHONDRIAL PTHR11773.SF1.pir AMINO_ACID_METABOLISM AA GCS-P2 PTHR11773.SF12.mod GLYCINE_CLEAVAGE_SYSTEM_P_PROTEIN PTHR11773.SF12.pir AMINO_ACID_METABOLISM AA GCS-T PTHR43757.mag.mod AMINOMETHYLTRANSFERASE PTHR43757.orig.30.pir AMINO_ACID_METABOLISM AA GCS-T PTHR43757.SF2.mod AMINOMETHYLTRANSFERASE,_MITOCHONDRIAL PTHR43757.SF2.pir AMINO_ACID_METABOLISM AA SHMT PTHR11680.mag.mod SERINE_HYDROXYMETHYLTRANSFERASE PTHR11680.orig.30.pir AMINO_ACID_METABOLISM AA SHMT PTHR11680.SF28.mod SERINE_HYDROXYMETHYLTRANSFERASE,_MITOCHONDRIAL PTHR11680.SF28.pir AMINO_ACID_METABOLISM AA ECH PTHR43802.mag.mod ENOYL-COA_HYDRATASE PTHR43802.orig.30.pir AMINO_ACID_METABOLISM AA ECH PTHR43802.SF1.mod ZGC:101569 PTHR43802.SF1.pir AMINO_ACID_METABOLISM AA ACAD PTHR43884.mag.mod ACYL-COA_DEHYDROGENASE PTHR43884.orig.30.pir AMINO_ACID_METABOLISM AA ACAD PTHR43884.SF1.mod SHORT/BRANCHED_CHAIN_SPECIFIC_ACYL-COA_DEHYDROGENASE,_MITOCHONDRIAL PTHR43884.SF1.pir AMINO_ACID_METABOLISM AA BaKDH-E1a PTHR43380.mag.mod 2-OXOISOVALERATE_DEHYDROGENASE_SUBUNIT_ALPHA,_MITOCHONDRIAL PTHR43380.orig.30.pir AMINO_ACID_METABOLISM AA BaKDH-E1a PTHR43380.SF1.mod 2-OXOISOVALERATE_DEHYDROGENASE_SUBUNIT_ALPHA,_MITOCHONDRIAL PTHR43380.SF1.pir AMINO_ACID_METABOLISM AA BaKDH-E1b PTHR42980.mag.mod 2-OXOISOVALERATE_DEHYDROGENASE_SUBUNIT_BETA-RELATED PTHR42980.orig.30.pir AMINO_ACID_METABOLISM AA BaKDH-E1b PTHR42980.SF1.mod 2-OXOISOVALERATE_DEHYDROGENASE_SUBUNIT_BETA,_MITOCHONDRIAL PTHR42980.SF1.pir AMINO_ACID_METABOLISM AA BaKDH-E2 PTHR43178.mag.mod DIHYDROLIPOAMIDE_ACETYLTRANSFERASE_COMPONENT_OF_PYRUVATE_DEHYDROGENASE_COMPLEX PTHR43178.orig.30.pir AMINO_ACID_METABOLISM AA BaKDH-E2 PTHR43178.SF5.mod LIPOAMIDE_ACYLTRANSFERASE_COMPONENT_OF_BRANCHED-CHAIN_ALPHA-KETO_ACID_DEHYDROGENASE_COMPLEX,_MITOCHONDRIAL PTHR43178.SF5.pir AMINO_ACID_METABOLISM AA BCAAT PTHR11825.mag.mod SUBGROUP_IIII_AMINOTRANSFERASE PTHR11825.orig.30.pir AMINO_ACID_METABOLISM AA BCAAT PTHR11825.SF44.mod BRANCHED-CHAIN-AMINO-ACID_AMINOTRANSFERASE PTHR11825.SF44.pir AMINO_ACID_METABOLISM AA 3HB-dehydrogenase PTHR43060.mag.mod 3-HYDROXYISOBUTYRATE_DEHYDROGENASE-LIKE_1,_MITOCHONDRIAL-RELATED PTHR43060.orig.30.pir AMINO_ACID_METABOLISM AA 3HB-dehydrogenase PTHR43060.SF15.mod 3-HYDROXYISOBUTYRATE_DEHYDROGENASE-LIKE_1,_MITOCHONDRIAL-RELATED PTHR43060.SF15.pir AMINO_ACID_METABOLISM AA hydroxymethylglutaryl-CoA_synthase PTHR43323.mag.mod 3-HYDROXY-3-METHYLGLUTARYL_COENZYME_A_SYNTHASE PTHR43323.orig.30.pir AMINO_ACID_METABOLISM AA hydroxymethylglutaryl-CoA_synthase PTHR43323.SF2.mod 3-HYDROXY-3-METHYLGLUTARYL_COENZYME_A_SYNTHASE PTHR43323.SF2.pir AMINO_ACID_METABOLISM AA MMSA-dehydrogenase PTHR43866.mag.mod MALONATE-SEMIALDEHYDE_DEHYDROGENASE PTHR43866.orig.30.pir AMINO_ACID_METABOLISM AA MMSA-dehydrogenase PTHR43866.SF3.mod METHYLMALONATE-SEMIALDEHYDE_DEHYDROGENASE_[ACYLATING],_MITOCHONDRIAL PTHR43866.SF3.pir AMINO_ACID_METABOLISM AA PCCa PTHR18866.mag.mod CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA_CARBOXYLASE PTHR18866.orig.30.pir AMINO_ACID_METABOLISM AA PCCa PTHR18866.SF33.mod METHYLCROTONOYL-COA_CARBOXYLASE_SUBUNIT_ALPHA,_MITOCHONDRIAL-RELATED PTHR18866.SF33.pir AMINO_ACID_METABOLISM AA PCCb PTHR43842.mag.mod PROPIONYL-COA_CARBOXYLASE_BETA_CHAIN PTHR43842.orig.30.pir AMINO_ACID_METABOLISM AA PCCb PTHR43842.SF2.mod PROPIONYL-COA_CARBOXYLASE_BETA_CHAIN-RELATED PTHR43842.SF2.pir AMINO_ACID_METABOLISM AA MM-CoA-epimerase PTHR43048.mag.mod METHYLMALONYL-COA_EPIMERASE PTHR43048.orig.30.pir AMINO_ACID_METABOLISM AA MM-CoA-epimerase PTHR43048.SF3.mod METHYLMALONYL-COA_EPIMERASE,_MITOCHONDRIAL PTHR43048.SF3.pir AMINO_ACID_METABOLISM AA MM-CoA-mutase PTHR48101.mag.mod METHYLMALONYL-COA_MUTASE,_MITOCHONDRIAL-RELATED PTHR48101.orig.30.pir AMINO_ACID_METABOLISM AA MM-CoA-mutase PTHR48101.SF4.mod METHYLMALONYL-COA_MUTASE,_MITOCHONDRIAL PTHR48101.SF4.pir AMINO_ACID_METABOLISM AA AGT PTHR45688.mag.mod - PTHR45688.orig.30.pir AMINO_ACID_METABOLISM AA AGT PTHR45688.SF3.mod ALANINE--GLYOXYLATE_AMINOTRANSFERASE_2,_MITOCHONDRIAL PTHR45688.SF3.pir AMINO_ACID_METABOLISM AA AST PTHR11879.mag.mod ASPARTATE_AMINOTRANSFERASE PTHR11879.orig.30.pir AMINO_ACID_METABOLISM AA AST PTHR11879.SF22.mod ASPARTATE_AMINOTRANSFERASE,_MITOCHONDRIAL PTHR11879.SF22.pir AMINO_ACID_METABOLISM AA AST PTHR11879.SF55.mod ASPARTATE_TRANSAMINASE PTHR11879.SF55.pir AMINO_ACID_METABOLISM AA ALT PTHR11751.mag.mod ALANINE_AMINOTRANSFERASE PTHR11751.orig.30.pir AMINO_ACID_METABOLISM AA ALT PTHR11751.SF29.mod AT04676P PTHR11751.SF29.pir AMINO_ACID_METABOLISM AA Cysteine_synthase? PTHR43797.mag.mod HOMOCYSTEINE/CYSTEINE_SYNTHASE PTHR43797.orig.30.pir AMINO_ACID_METABOLISM AA Cysteine_synthase? PTHR43797.SF2.mod HOMOCYSTEINE/CYSTEINE_SYNTHASE PTHR43797.SF2.pir AMINO_ACID_METABOLISM AA Pyrroline-5-carboxylate_reductase PTHR11645.mag.mod PYRROLINE-5-CARBOXYLATE_REDUCTASE PTHR11645.orig.30.pir AMINO_ACID_METABOLISM AA Pyrroline-5-carboxylate_reductase PTHR11645.SF0.mod PYRROLINE-5-CARBOXYLATE_REDUCTASE_3 PTHR11645.SF0.pir AMINO_ACID_METABOLISM AA Delta-1-pyrroline-5-carboxylate_dehydrogenase PTHR42862.mag.mod DELTA-1-PYRROLINE-5-CARBOXYLATE_DEHYDROGENASE_1,_ISOFORM_A-RELATED PTHR42862.orig.30.pir AMINO_ACID_METABOLISM AA Delta-1-pyrroline-5-carboxylate_dehydrogenase PTHR42862.SF1.mod DELTA-1-PYRROLINE-5-CARBOXYLATE_DEHYDROGENASE_2,_ISOFORM_A-RELATED PTHR42862.SF1.pir AMINO_ACID_METABOLISM AA Citrate_Lyase PTHR32308.mag.mod LYASE_BETA_SUBUNIT,_PUTATIVE_(AFU_ORTHOLOGUE_AFUA_4G13030)-RELATED PTHR32308.orig.30.pir AMINO_ACID_METABOLISM AA Citrate_Lyase PTHR32308.SF1.mod HPCH_HPAI_DOMAIN-CONTAINING_PROTEIN PTHR32308.SF1.pir AMINO_ACID_METABOLISM AA Citrate_Lyase PTHR32308.SF10.mod CITRATE_LYASE_SUBUNIT_BETA PTHR32308.SF10.pir AMINO_ACID_METABOLISM AA Citrate_Lyase PTHR11105.mag.mod CITRATE_LYASE_SUBUNIT_BETA-RELATED PTHR11105.orig.30.pir AMINO_ACID_METABOLISM AA Citrate_Lyase PTHR11105.SF0.mod CITRAMALYL-COA_LYASE,_MITOCHONDRIAL PTHR11105.SF0.pir AMINO_ACID_METABOLISM AA Glutamate_DH PTHR11606.mag.mod GLUTAMATE_DEHYDROGENASE PTHR11606.orig.30.pir AMINO_ACID_METABOLISM AA Glutamate_DH PTHR11606.SF13.mod GLUTAMATE_DEHYDROGENASE_1,_MITOCHONDRIAL PTHR11606.SF13.pir AMINO_ACID_METABOLISM AA thiosulfate/3-mercaptopyruvate_sulfurtransferase PTHR11364.mag.mod THIOSULFATE_SULFERTANSFERASE PTHR11364.orig.30.pir AMINO_ACID_METABOLISM AA thiosulfate/3-mercaptopyruvate_sulfurtransferase PTHR11364.SF27.mod SULFURTRANSFERASE PTHR11364.SF27.pir AMINO_ACID_METABOLISM AA ThrC_-_bussel_extension PTHR48078.mag.mod THREONINE_DEHYDRATASE,_MITOCHONDRIAL-RELATED PTHR48078.orig.30.pir AMINO_ACID_METABOLISM AA ThrC_-_bussel_extension PTHR48078.SF6.mod ACT_DOMAIN-CONTAINING_PROTEIN PTHR48078.SF6.pir AMINO_ACID_METABOLISM KETONE ACAT PTHR18919.mag.mod ACETYL-COA_C-ACYLTRANSFERASE PTHR18919.orig.30.pir AMINO_ACID_METABOLISM KETONE ACAT PTHR18919.SF156.mod ACETYL-COA_ACETYLTRANSFERASE,_MITOCHONDRIAL PTHR18919.SF156.pir AMINO_ACID_METABOLISM KETONE SCOT PTHR13707.mag.mod KETOACID-COENZYME_A_TRANSFERASE PTHR13707.orig.30.pir AMINO_ACID_METABOLISM KETONE SCOT PTHR13707.SF23.mod SUCCINYL-COA:3-KETOACID-COENZYME_A_TRANSFERASE PTHR13707.SF23.pir AMINO_ACID_METABOLISM KETONE Ketobutyrate_lyase PTHR13693.mag.mod CLASS_II_AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE_SYNTHASE PTHR13693.orig.30.pir AMINO_ACID_METABOLISM KETONE Ketobutyrate_lyase PTHR13693.SF102.mod 2-AMINO-3-KETOBUTYRATE_COENZYME_A_LIGASE,_MITOCHONDRIAL PTHR13693.SF102.pir
Fatty acid metabolism
FATTY_ACID_METABOLISM FATTY_ACID 4-aminobutyrate_transaminase PTHR43206.SF1.mod 4-AMINOBUTYRATE_AMINOTRANSFERASE,_MITOCHONDRIAL PTHR43206.SF1.pir FATTY_ACID_METABOLISM FATTY_ACID 4-aminobutyrate_transaminase PTHR43206.mag.mod AMINOTRANSFERASE PTHR43206.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID glutamate_dehydrogenase_(NADP) PTHR43571.mag.mod NADP-SPECIFIC_GLUTAMATE_DEHYDROGENASE_1-RELATED PTHR43571.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID glutamate_dehydrogenase_(NADP) PTHR43571.SF1.mod NADP-SPECIFIC_GLUTAMATE_DEHYDROGENASE_1-RELATED PTHR43571.SF1.pir FATTY_ACID_METABOLISM FATTY_ACID Succinate_semialdehyde_dehydrogenase_(NADP) PTHR43217.mag.mod SUCCINATE_SEMIALDEHYDE_DEHYDROGENASE_[NAD(P)+]_SAD PTHR43217.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID Succinate_semialdehyde_dehydrogenase_(NADP) PTHR43217.SF1.mod SUCCINATE_SEMIALDEHYDE_DEHYDROGENASE_[NAD(P)+]_SAD PTHR43217.SF1.pir FATTY_ACID_METABOLISM FATTY_ACID 2-oxoglutarate_dehydrogenase,_E1_component PTHR23152.mag.mod 2-OXOGLUTARATE_DEHYDROGENASE PTHR23152.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID 2-oxoglutarate_dehydrogenase,_E1_component PTHR23152.SF4.mod 2-OXOGLUTARATE_DEHYDROGENASE_E1_COMPONENT_DHKTD1,_MITOCHONDRIAL-RELATED PTHR23152.SF4.pir FATTY_ACID_METABOLISM FATTY_ACID 2-oxoglutarate_dehydrogenase,_E2_component PTHR43416.SF5.mod DIHYDROLIPOYLLYSINE-RESIDUE_SUCCINYLTRANSFERASE_COMPONENT_OF_2-OXOGLUTARATE_DEHYDROGENASE_COMPLEX,_MITOCHONDRIAL PTHR43416.SF5.pir FATTY_ACID_METABOLISM FATTY_ACID 2-oxoglutarate_dehydrogenase,_E2_component PTHR43416.mag.mod DIHYDROLIPOYLLYSINE-RESIDUE_SUCCINYLTRANSFERASE_COMPONENT_OF_2-OXOGLUTARATE_DEHYDROGENASE_COMPLEX,_MITOCHONDRIAL-RELATED PTHR43416.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID 2-oxoglutarate_dehydrogenase,_E2_component PTHR43416.SF5.mod DIHYDROLIPOYLLYSINE-RESIDUE_SUCCINYLTRANSFERASE_COMPONENT_OF_2-OXOGLUTARATE_DEHYDROGENASE_COMPLEX,_MITOCHONDRIAL PTHR43416.SF5.pir FATTY_ACID_METABOLISM FATTY_ACID 2-oxoglutarate_dehydrogenase,_E2_component PTHR43416.mag.mod DIHYDROLIPOYLLYSINE-RESIDUE_SUCCINYLTRANSFERASE_COMPONENT_OF_2-OXOGLUTARATE_DEHYDROGENASE_COMPLEX,_MITOCHONDRIAL-RELATED PTHR43416.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID kynurenine/alpha-aminoadipate_aminotransferase PTHR42790.mag.mod AMINOTRANSFERASE PTHR42790.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID kynurenine/alpha-aminoadipate_aminotransferase PTHR42790.SF3.mod KYNURENINE/ALPHA-AMINOADIPATE_AMINOTRANSFERASE,_MITOCHONDRIAL PTHR42790.SF3.pir FATTY_ACID_METABOLISM FATTY_ACID tyrosine_aminotransferase PTHR45744.mag.mod TYROSINE_AMINOTRANSFERASE PTHR45744.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID tyrosine_aminotransferase PTHR45744.SF2.mod TYROSINE_AMINOTRANSFERASE PTHR45744.SF2.pir FATTY_ACID_METABOLISM FATTY_ACID S-adenosylmethionine_synthetase PTHR11964.SF1.mod S-ADENOSYLMETHIONINE_SYNTHASE PTHR11964.SF1.pir FATTY_ACID_METABOLISM FATTY_ACID S-adenosylmethionine_synthetase PTHR11964.mag.mod S-ADENOSYLMETHIONINE_SYNTHETASE PTHR11964.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID Saccharopine_dehydrogenase PTHR11133.SF25.mod ALPHA-AMINOADIPIC_SEMIALDEHYDE_SYNTHASE,_MITOCHONDRIAL PTHR11133.SF25.pir FATTY_ACID_METABOLISM FATTY_ACID Saccharopine_dehydrogenase PTHR11133.mag.mod SACCHAROPINE_DEHYDROGENASE PTHR11133.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID Acyl-CoA_synthetase PTHR42793.mag.mod COA_BINDING_DOMAIN_CONTAINING_PROTEIN PTHR42793.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID Acyl-CoA_synthetase PTHR42793.SF1.mod PEPTIDYL-LYSINE_N-ACETYLTRANSFERASE_PATZ PTHR42793.SF1.pir FATTY_ACID_METABOLISM FATTY_ACID Pyridine_nucleotide_disulphide_oxidoreductase PTHR43429.SF3.mod NITRITE_REDUCTASE_[NAD(P)H] PTHR43429.SF3.pir FATTY_ACID_METABOLISM FATTY_ACID Pyridine_nucleotide_disulphide_oxidoreductase PTHR43429.mag.mod PYRIDINE_NUCLEOTIDE-DISULFIDE_OXIDOREDUCTASE_DOMAIN-CONTAINING PTHR43429.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID Delta-1-pyrroline-5-carboxylate_dehydrogenase PTHR43521.mag.mod ALPHA-AMINOADIPIC_SEMIALDEHYDE_DEHYDROGENASE PTHR43521.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID Delta-1-pyrroline-5-carboxylate_dehydrogenase PTHR43521.SF7.mod DELTA-1-PYRROLINE-5-CARBOXYLATE_DEHYDROGENASE_12A1,_MITOCHONDRIAL PTHR43521.SF7.pir FATTY_ACID_METABOLISM FATTY_ACID Acetyl-CoA_carboxylase PTHR45728.SF3.mod ACETYL-COA_CARBOXYLASE PTHR45728.SF3.pir FATTY_ACID_METABOLISM FATTY_ACID Acetyl-CoA_carboxylase PTHR45728.mag.mod ACETYL-COA_CARBOXYLASE,_ISOFORM_A PTHR45728.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID long-chain-fatty-acid-coA-ligase_(1) PTHR43272.SF32.mod AMP-BINDING_DOMAIN-CONTAINING_PROTEIN PTHR43272.SF32.pir FATTY_ACID_METABOLISM FATTY_ACID long-chain-fatty-acid-coA-ligase_(1) PTHR43272.mag.mod LONG-CHAIN-FATTY-ACID--COA_LIGASE PTHR43272.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID long-chain-fatty-acid-coA-ligase_(2) PTHR43272.SF32.mod AMP-BINDING_DOMAIN-CONTAINING_PROTEIN PTHR43272.SF32.pir FATTY_ACID_METABOLISM FATTY_ACID long-chain-fatty-acid-coA-ligase_(2) PTHR43272.mag.mod LONG-CHAIN-FATTY-ACID--COA_LIGASE PTHR43272.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID enoyl-[acyl-carrier-protein]_reductase PTHR43981.mag.mod ENOYL-[ACYL-CARRIER-PROTEIN]_REDUCTASE,_MITOCHONDRIAL PTHR43981.orig.30.pir FATTY_ACID_METABOLISM FATTY_ACID enoyl-[acyl-carrier-protein]_reductase PTHR43981.SF2.mod ENOYL-[ACYL-CARRIER-PROTEIN]_REDUCTASE,_MITOCHONDRIAL PTHR43981.SF2.pir FATTY_ACID_METABOLISM FATTY_ACID enoyl-[acyl-carrier-protein]_reductase PTHR43981.SF9.mod ENOYL-[ACYL-CARRIER-PROTEIN]_REDUCTASE,_MITOCHONDRIAL PTHR43981.SF9.pir
Mitochondrial carriers
SOLUTE_CARRIERS CARRIERS arginine/ornithine_transport_system_ATPase PTHR23408.mag.mod METHYLMALONYL-COA_MUTASE PTHR23408.orig.30.pir SOLUTE_CARRIERS CARRIERS arginine/ornithine_transport_system_ATPase PTHR23408.SF3.mod METHYLMALONIC_ACIDURIA_TYPE_A_PROTEIN,_MITOCHONDRIAL PTHR23408.SF3.pir SOLUTE_CARRIERS CARRIERS Mitochondrial_carrier_family_protein_(1) PTHR24089.mag.mod SOLUTE_CARRIER_FAMILY_25 PTHR24089.orig.30.pir SOLUTE_CARRIERS CARRIERS Mitochondrial_carrier_family_protein_(1) PTHR24089.SF246.mod SOLUTE_CARRIER_FAMILY_25_MEMBER_43 PTHR24089.SF246.pir SOLUTE_CARRIERS CARRIERS Mitochondrial_carrier_family_protein_(2) PTHR46181.mag.mod MITOCHONDRIAL_GLYCINE_TRANSPORTER PTHR46181.orig.30.pir SOLUTE_CARRIERS CARRIERS Mitochondrial_carrier_family_protein_(2) PTHR46181.SF3.mod MITOCHONDRIAL_GLYCINE_TRANSPORTER PTHR46181.SF3.pir SOLUTE_CARRIERS CARRIERS Mitochondrial_carrier_family_protein_(3) PTHR47567.mag.mod MITOCHONDRIAL_SUBSTRATE/SOLUTE_CARRIER PTHR47567.orig.30.pir SOLUTE_CARRIERS CARRIERS Mitochondrial_carrier_family_protein_(3) PTHR47567.SF1.mod EPIMERASE_DOMAIN-CONTAINING_PROTEIN PTHR47567.SF1.pir SOLUTE_CARRIERS CARRIERS Mitochondrial_carrier_family_protein_(4) PTHR45635.mag.mod ADP,ATP_CARRIER_PROTEIN_1-RELATED-RELATED PTHR45635.orig.30.pir SOLUTE_CARRIERS CARRIERS Mitochondrial_carrier_family_protein_(4) PTHR45635.SF14.mod ADP/ATP_TRANSLOCASE PTHR45635.SF14.pir SOLUTE_CARRIERS CARRIERS Aralar_Asp/Glu_carrier PTHR45678.mag.mod MITOCHONDRIAL_2-OXODICARBOXYLATE_CARRIER_1-RELATED PTHR45678.orig.30.pir SOLUTE_CARRIERS CARRIERS Aralar_Asp/Glu_carrier PTHR45678.SF9.mod CALCIUM-BINDING_MITOCHONDRIAL_CARRIER_PROTEIN_ARALAR1 PTHR45678.SF9.pir
Mitochondrial import
PROTEIN_IMPORT_AND_FOLDING IMPORT Tom40 PTHR10802.mag.mod MITOCHONDRIAL_IMPORT_RECEPTOR_SUBUNIT_TOM40 PTHR10802.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tom40 PTHR10802.SF2.mod MITOCHONDRIAL_IMPORT_RECEPTOR_SUBUNIT_TOM40_HOMOLOG_1-RELATED PTHR10802.SF2.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Sam50 PTHR12815.SF18.mod SORTING_AND_ASSEMBLY_MACHINERY_COMPONENT_50_HOMOLOG PTHR12815.SF18.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Sam50 PTHR12815.mag.mod SORTING_AND_ASSEMBLY_MACHINERY_SAMM50_PROTEIN_FAMILY_MEMBER PTHR12815.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Mia40 PTHR21622.SF0.mod AU015836_PROTEIN-RELATED PTHR21622.SF0.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Mia40 PTHR21622.mag.mod COILED-COIL-HELIX-COILED-COIL-HELIX_DOMAIN_CONTAINING_4 PTHR21622.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim8/Tim13 PTHR19338.mag.mod TRANSLOCASE_OF_INNER_MITOCHONDRIAL_MEMBRANE_13_HOMOLOG PTHR19338.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim8/Tim13 PTHR19338.SF1.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM8_A-B-RELATED PTHR19338.SF1.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim8/Tim13 PTHR19338.SF4.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT PTHR19338.SF4.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim9 PTHR13172.SF5.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM9 PTHR13172.SF5.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim9 PTHR13172.mag.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM9B PTHR13172.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim10 PTHR11038.mag.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM10 PTHR11038.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim10 PTHR11038.SF16.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM10 PTHR11038.SF16.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim22 PTHR14110.mag.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM22 PTHR14110.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim22 PTHR14110.SF0.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM22 PTHR14110.SF0.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim23 PTHR15371.SF0.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM23 PTHR15371.SF0.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim23 PTHR15371.mag.mod TIM23 PTHR15371.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Pam18/Tim14 PTHR12763.mag.mod UNCHARACTERIZED PTHR12763.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Pam18/Tim14 PTHR12763.SF28.mod GEO10507P1-RELATED PTHR12763.SF28.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Pam18/Tim14 PTHR12763.SF42.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM14-3-LIKE PTHR12763.SF42.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Pam16/Tim16 PTHR12388.mag.mod MITOCHONDRIA_ASSOCIATED_GRANULOCYTE_MACROPHAGE_CSF_SIGNALING_MOLECULE PTHR12388.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Pam16/Tim16 PTHR12388.SF0.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM16 PTHR12388.SF0.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Pam17 PTHR28021.mag.mod PRESEQUENCE_TRANSLOCATED-ASSOCIATED_MOTOR_SUBUNIT_PAM17,_MITOCHONDRIAL PTHR28021.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Pam17 PTHR28021.SF1.mod PRESEQUENCE_TRANSLOCATED-ASSOCIATED_MOTOR_SUBUNIT_PAM17,_MITOCHONDRIAL PTHR28021.SF1.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim17 PTHR10485.SF0.mod AT05822P-RELATED PTHR10485.SF0.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim17 PTHR10485.mag.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM-17 PTHR10485.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim44 PTHR10721.mag.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM44 PTHR10721.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim44 PTHR10721.SF1.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM44 PTHR10721.SF1.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim44 PTHR47652.mag.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM44 PTHR47652.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Tim44 PTHR47652.SF3.mod MITOCHONDRIAL_IMPORT_INNER_MEMBRANE_TRANSLOCASE_SUBUNIT_TIM44 PTHR47652.SF3.pir PROTEIN_IMPORT_AND_FOLDING IMPORT mtHsp70/SSQ1 PTHR19375.mag.mod HEAT_SHOCK_PROTEIN_70KDA PTHR19375.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT mtHsp70/SSQ1 PTHR19375.SF184.mod STRESS-70_PROTEIN,_MITOCHONDRIAL PTHR19375.SF184.pir PROTEIN_IMPORT_AND_FOLDING IMPORT mtHsp70/SSQ1 PTHR19375.SF197.mod IRON-SULFUR_CLUSTER_BIOGENESIS_CHAPERONE,_MITOCHONDRIAL PTHR19375.SF197.pir PROTEIN_IMPORT_AND_FOLDING IMPORT mtHsp70/SSQ1 PTHR19375.SF510.mod HEAT_SHOCK_70_KDA_PROTEIN,_MITOCHONDRIAL PTHR19375.SF510.pir PROTEIN_IMPORT_AND_FOLDING IMPORT GrpE/Mge1 PTHR21237.mag.mod GRPE_PROTEIN PTHR21237.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT GrpE/Mge1 PTHR21237.SF23.mod GRPE_PROTEIN_HOMOLOG,_MITOCHONDRIAL PTHR21237.SF23.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Mitochondrial_chaperone_BCS-1 PTHR23070.mag.mod BCS1_AAA-TYPE_ATPASE PTHR23070.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Mitochondrial_chaperone_BCS-1 PTHR23070.SF144.mod MITOCHONDRIAL_CHAPERONE_BCS1 PTHR23070.SF144.pir PROTEIN_IMPORT_AND_FOLDING IMPORT MPPa PTHR11851.mag.mod METALLOPROTEASE PTHR11851.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT MPPa PTHR11851.SF49.mod MITOCHONDRIAL-PROCESSING_PEPTIDASE_SUBUNIT_ALPHA PTHR11851.SF49.pir PROTEIN_IMPORT_AND_FOLDING IMPORT MPPb PTHR11851.SF149.mod GH01077P PTHR11851.SF149.pir PROTEIN_IMPORT_AND_FOLDING IMPORT MPPb PTHR11851.mag.mod METALLOPROTEASE PTHR11851.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Cpn10 PTHR10772.mag.mod 10_KDA_HEAT_SHOCK_PROTEIN PTHR10772.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Cpn10 PTHR10772.SF0.mod 10_KDA_HEAT_SHOCK_PROTEIN,_MITOCHONDRIAL PTHR10772.SF0.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Cpn60 PTHR45633.mag.mod 60_KDA_HEAT_SHOCK_PROTEIN,_MITOCHONDRIAL PTHR45633.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Cpn60 PTHR45633.SF3.mod 60_KDA_HEAT_SHOCK_PROTEIN,_MITOCHONDRIAL PTHR45633.SF3.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Metaxin PTHR12289.SF41.mod FAILED_AXON_CONNECTIONS-RELATED PTHR12289.SF41.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Metaxin PTHR12289.mag.mod METAXIN_RELATED PTHR12289.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT UPS1 PTHR11158.mag.mod MSF1/PX19_RELATED PTHR11158.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT UPS1 PTHR11158.SF17.mod PROTEIN_SLOWMO PTHR11158.SF17.pir PROTEIN_IMPORT_AND_FOLDING IMPORT UPS2 PTHR11158.mag.mod MSF1/PX19_RELATED PTHR11158.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT UPS2 PTHR11158.SF30.mod PRELI/MSF1_DOMAIN-CONTAINING_PROTEIN PTHR11158.SF30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Mmp37/Tam41 PTHR13619.SF0.mod PHOSPHATIDATE_CYTIDYLYLTRANSFERASE,_MITOCHONDRIAL PTHR13619.SF0.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Mmp37/Tam41 PTHR13619.mag.mod UNCHARACTERIZED PTHR13619.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Prohibitin PTHR23222.mag.mod PROHIBITIN PTHR23222.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Prohibitin PTHR23222.SF0.mod PROHIBITIN PTHR23222.SF0.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Presequence_protease PTHR43016.mag.mod PRESEQUENCE_PROTEASE PTHR43016.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Presequence_protease PTHR43016.SF13.mod PRESEQUENCE_PROTEASE,_MITOCHONDRIAL PTHR43016.SF13.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Fumarate_reductase/Osm1 PTHR43400.SF7.mod FAD_BINDING_2_DOMAIN-CONTAINING_PROTEIN PTHR43400.SF7.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Fumarate_reductase/Osm1 PTHR43400.mag.mod FUMARATE_REDUCTASE PTHR43400.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Fumarate_Hydratase PTHR11444.SF1.mod FUMARATE_HYDRATASE,_MITOCHONDRIAL PTHR11444.SF1.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Fumarate_Hydratase PTHR11444.SF22.mod FUMARATE_HYDRATASE_CLASS_II PTHR11444.SF22.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Fumarate_Hydratase PTHR11444.mag.mod ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE_LYASE PTHR11444.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Atp23 PTHR21711.mag.mod MITOCHONDRIAL_INNER_MEMBRANE_PROTEASE PTHR21711.orig.30.pir PROTEIN_IMPORT_AND_FOLDING IMPORT Atp23 PTHR21711.SF0.mod MITOCHONDRIAL_INNER_MEMBRANE_PROTEASE_ATP23_HOMOLOG PTHR21711.SF0.pir
Reactive Oxygen Species and Oxygen detoxification
ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 flavoprotein_A_-_ferredoxin_fused_to_N-terminus PTHR43717.mag.mod ANAEROBIC_NITRIC_OXIDE_REDUCTASE_FLAVORUBREDOXIN PTHR43717.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 flavoprotein_A_-_ferredoxin_fused_to_N-terminus PTHR43717.SF1.mod ANAEROBIC_NITRIC_OXIDE_REDUCTASE_FLAVORUBREDOXIN PTHR43717.SF1.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 peroxiredoxin_V PTHR10430.mag.mod PEROXIREDOXIN PTHR10430.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 peroxiredoxin_V PTHR10430.SF16.mod PEROXIREDOXIN-5,_MITOCHONDRIAL PTHR10430.SF16.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 thioredoxin_(1) PTHR45663.mag.mod GEO12009P1 PTHR45663.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 thioredoxin_(1) PTHR45663.SF11.mod GEO12009P1 PTHR45663.SF11.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 superoxide_dismutase PTHR42769.mag.mod SUPEROXIDE_DISMUTASE PTHR42769.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 superoxide_dismutase PTHR42769.SF3.mod SUPEROXIDE_DISMUTASE_[FE]_2,_CHLOROPLASTIC PTHR42769.SF3.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 NADPH-dependent_thioredoxin_reductase_1_(selenoprotein) PTHR42737.mag.mod GLUTATHIONE_REDUCTASE PTHR42737.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 NADPH-dependent_thioredoxin_reductase_1_(selenoprotein) PTHR42737.SF3.mod THIOREDOXIN-DISULFIDE_REDUCTASE PTHR42737.SF3.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 Amoebozoa-type';_FDP_fused_with_NADH_oxidase_domain PTHR32145.mag.mod DIFLAVIN_FLAVOPROTEIN_A_2-RELATED PTHR32145.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 Amoebozoa-type';_FDP_fused_with_NADH_oxidase_domain PTHR32145.SF11.mod DIFLAVIN_FLAVOPROTEIN_A_2-RELATED PTHR32145.SF11.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 Glutathione_repair__https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402446/ PTHR23088.mag.mod NITRILASE-RELATED PTHR23088.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 Glutathione_repair__https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402446/ PTHR23088.SF30.mod OMEGA-AMIDASE_NIT2 PTHR23088.SF30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 Nitroreductase PTHR43673.mag.mod NAD(P)H_NITROREDUCTASE_YDGI-RELATED PTHR43673.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 Nitroreductase PTHR43673.SF2.mod NITROREDUCTASE_FAMILY_PROTEIN PTHR43673.SF2.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 RBR PTHR43865.mag.mod RUBRERYTHRIN-RELATED PTHR43865.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 RBR PTHR43865.SF1.mod RUBRERYTHRIN-RELATED PTHR43865.SF1.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 Glutaredoxin_ PTHR10293.mag.mod GLUTAREDOXIN_FAMILY_MEMBER PTHR10293.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 Glutaredoxin_ PTHR10293.SF16.mod GLUTAREDOXIN-RELATED_PROTEIN_5,_MITOCHONDRIAL PTHR10293.SF16.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 OsmC/Ohr PTHR35368.mag.mod HYDROPEROXIDE_REDUCTASE PTHR35368.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 OsmC/Ohr PTHR35368.SF1.mod HYDROPEROXIDE_REDUCTASE PTHR35368.SF1.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 Thioredoxin PTHR43601.mag.mod THIOREDOXIN,_MITOCHONDRIAL PTHR43601.orig.30.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 Thioredoxin PTHR43601.SF3.mod THIOREDOXIN,_MITOCHONDRIAL PTHR43601.SF3.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 NADH_oxidase PTHR43429.SF1.mod NAD(P)H_SULFUR_OXIDOREDUCTASE_(COA-DEPENDENT) PTHR43429.SF1.pir ROS_AND_OXYGEN_DETOXIFICATION ROS_O2 NADH_oxidase PTHR43429.mag.mod PYRIDINE_NUCLEOTIDE-DISULFIDE_OXIDOREDUCTASE_DOMAIN-CONTAINING PTHR43429.orig.30.pir
Cell division
Kinetochore
CHROMOSOMAL_PASSENGER_COMPLEX CPC Incenp PTHR13142.mag.mod INNER_CENTROMERE_PROTEIN PTHR13142.orig.30.pir CHROMOSOMAL_PASSENGER_COMPLEX CPC Incenp PTHR13142.SF1.mod INNER_CENTROMERE_PROTEIN PTHR13142.SF1.pir CHROMOSOMAL_PASSENGER_COMPLEX CPC Survivin PTHR46771.mag.mod DETERIN PTHR46771.orig.30.pir CHROMOSOMAL_PASSENGER_COMPLEX CPC Survivin PTHR46771.SF5.mod DETERIN PTHR46771.SF5.pir CHROMOSOMAL_PASSENGER_COMPLEX CPC Shugoshin PTHR21577.mag.mod SHUGOSHIN PTHR21577.orig.30.pir CHROMOSOMAL_PASSENGER_COMPLEX CPC Shugoshin PTHR21577.SF3.mod SHUGOSHIN_1-RELATED PTHR21577.SF3.pir CHROMOSOMAL_PASSENGER_COMPLEX CPC Aurora PTHR24350.mag.mod SERINE/THREONINE-PROTEIN_KINASE_IAL-RELATED PTHR24350.orig.30.pir CHROMOSOMAL_PASSENGER_COMPLEX CPC Aurora PTHR24350.SF0.mod AURORA_KINASE PTHR24350.SF0.pir CHROMOSOMAL_PASSENGER_COMPLEX CPC Aurora PTHR24350.SF5.mod AURORA_KINASE_A PTHR24350.SF5.pir CHROMOSOMAL_PASSENGER_COMPLEX CPC Aurora PTHR24350.SF24.mod AURORA_KINASE_B PTHR24350.SF24.pir CHROMOSOMAL_PASSENGER_COMPLEX CPC Borealin PTHR16040.mag.mod AUSTRALIN,_ISOFORM_A-RELATED PTHR16040.orig.30.pir CHROMOSOMAL_PASSENGER_COMPLEX CPC Borealin PTHR16040.SF6.mod BOREALIN PTHR16040.SF6.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpA PTHR45810.mag.mod HISTONE_H3.2 PTHR45810.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpA PTHR45810.SF14.mod CENTROMERE_PROTEIN_A PTHR45810.SF14.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpC PTHR16684.mag.mod CENTROMERE_PROTEIN_C PTHR16684.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpC PTHR16684.SF12.mod CENTROMERE_PROTEIN_C PTHR16684.SF12.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpH PTHR48122.mag.mod CENTROMERE_PROTEIN_H PTHR48122.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpH PTHR48122.SF1.mod CENTROMERE_PROTEIN_H PTHR48122.SF1.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpI PTHR48208.mag.mod CENTROMERE_PROTEIN_I PTHR48208.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpI PTHR48208.SF2.mod CENTROMERE_PROTEIN_I PTHR48208.SF2.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpK PTHR14401.mag.mod CENTROMERE_PROTEIN_K PTHR14401.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpK PTHR14401.SF6.mod CENTROMERE_PROTEIN_K PTHR14401.SF6.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpM PTHR34436.mag.mod CENTROMERE_PROTEIN_M PTHR34436.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpM PTHR34436.SF1.mod CENTROMERE_PROTEIN_M PTHR34436.SF1.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpL PTHR31740.mag.mod CENTROMERE_PROTEIN_L PTHR31740.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpL PTHR31740.SF2.mod CENTROMERE_PROTEIN_L PTHR31740.SF2.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpN PTHR46790.mag.mod CENTROMERE_PROTEIN_N PTHR46790.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpN PTHR46790.SF1.mod CENTROMERE_PROTEIN_N PTHR46790.SF1.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpO PTHR14582.mag.mod INNER_KINETOCHORE_SUBUNIT_MAL2 PTHR14582.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpO PTHR14582.SF1.mod CENTROMERE_PROTEIN_O PTHR14582.SF1.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpP PTHR28577.mag.mod CENTROMERE_PROTEIN_P PTHR28577.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpP PTHR28577.SF1.mod CENTROMERE_PROTEIN_P PTHR28577.SF1.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpQ PTHR31345.mag.mod CENTROMERE_PROTEIN_Q PTHR31345.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpQ PTHR31345.SF3.mod CENTROMERE_PROTEIN_Q PTHR31345.SF3.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpU PTHR32222.mag.mod CENTROMERE_PROTEIN_U PTHR32222.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpU PTHR32222.SF1.mod CENTROMERE_PROTEIN_U PTHR32222.SF1.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpT PTHR46904.mag.mod CENTROMERE_PROTEIN_T PTHR46904.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpT PTHR46904.SF1.mod CENTROMERE_PROTEIN_T PTHR46904.SF1.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpW PTHR34832.mag.mod CENTROMERE_PROTEIN_W PTHR34832.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpW PTHR34832.SF1.mod CENTROMERE_PROTEIN_W PTHR34832.SF1.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpX PTHR28680.mag.mod CENTROMERE_PROTEIN_X PTHR28680.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpX PTHR28680.SF1.mod CENTROMERE_PROTEIN_X PTHR28680.SF1.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpS PTHR22980.mag.mod CORTISTATIN PTHR22980.orig.30.pir CONSTITUTIVE_CENTROMERE_ASSOCIATED_NETWORK CCAN CenpS PTHR22980.SF0.mod CENTROMERE_PROTEIN_S PTHR22980.SF0.pir LINKER MIS12 Mis12 PTHR14527.mag.mod PROTEIN_MIS12_HOMOLOG PTHR14527.orig.30.pir LINKER MIS12 Mis12 PTHR14527.SF2.mod PROTEIN_MIS12_HOMOLOG PTHR14527.SF2.pir LINKER MIS12 Nnf1 PTHR15459.mag.mod POLYAMINE-MODULATED_FACTOR_1 PTHR15459.orig.30.pir LINKER MIS12 Nnf1 PTHR15459.SF3.mod POLYAMINE-MODULATED_FACTOR_1 PTHR15459.SF3.pir LINKER MIS12 Dsn1 PTHR14778.mag.mod KINETOCHORE-ASSOCIATED_PROTEIN_DSN1_HOMOLOG PTHR14778.orig.30.pir LINKER MIS12 Dsn1 PTHR14778.SF2.mod KINETOCHORE-ASSOCIATED_PROTEIN_DSN1_HOMOLOG PTHR14778.SF2.pir LINKER MIS12 Csm1 PTHR28006.mag.mod MONOPOLIN_COMPLEX_SUBUNIT_CSM1 PTHR28006.orig.30.pir LINKER MIS12 Csm1 PTHR28006.SF1.mod MONOPOLIN_COMPLEX_SUBUNIT_PCS1 PTHR28006.SF1.pir NDC80_COMPLEX NDC80 Ndc80 PTHR10643.mag.mod KINETOCHORE_PROTEIN_NDC80 PTHR10643.orig.30.pir NDC80_COMPLEX NDC80 Ndc80 PTHR10643.SF2.mod KINETOCHORE_PROTEIN_NDC80_HOMOLOG PTHR10643.SF2.pir NDC80_COMPLEX NDC80 Ndc80 PTHR46681.mag.mod KINETOCHORE_PROTEIN_NDC80_HOMOLOG PTHR46681.orig.30.pir NDC80_COMPLEX NDC80 Ndc80 PTHR46681.SF1.mod KINETOCHORE_PROTEIN_NDC80_HOMOLOG PTHR46681.SF1.pir NDC80_COMPLEX NDC80 Nuf2 PTHR21650.mag.mod MEMBRALIN/KINETOCHORE_PROTEIN_NUF2 PTHR21650.orig.30.pir NDC80_COMPLEX NDC80 Nuf2 PTHR21650.SF2.mod KINETOCHORE_PROTEIN_NUF2 PTHR21650.SF2.pir NDC80_COMPLEX NDC80 Spc24 PTHR35730.mag.mod KINETOCHORE_PROTEIN_SPC24_HOMOLOG-RELATED PTHR35730.orig.30.pir NDC80_COMPLEX NDC80 Spc24 PTHR35730.SF2.mod KINETOCHORE_PROTEIN_SPC24_HOMOLOG-RELATED PTHR35730.SF2.pir NDC80_COMPLEX NDC80 Spc24 PTHR22142.mag.mod UNCHARACTERIZED PTHR22142.orig.30.pir NDC80_COMPLEX NDC80 Spc24 PTHR22142.SF2.mod KINETOCHORE_PROTEIN_SPC24 PTHR22142.SF2.pir NDC80_COMPLEX NDC80 Spc25 PTHR14281.mag.mod KINETOCHORE_PROTEIN_SPC25-RELATED PTHR14281.orig.30.pir NDC80_COMPLEX NDC80 Spc25 PTHR14281.SF0.mod KINETOCHORE_PROTEIN_SPC25 PTHR14281.SF0.pir NDC80_COMPLEX NDC80 Spc25 PTHR14281.SF1.mod KINETOCHORE_PROTEIN_SPC25 PTHR14281.SF1.pir NDC80_COMPLEX NDC80 Spc25 PTHR14281.SF2.mod KINETOCHORE_PROTEIN_SPC25 PTHR14281.SF2.pir NDC80_COMPLEX NDC80 Spc25 PTHR14281.SF3.mod KINETOCHORE_PROTEIN_SPC25 PTHR14281.SF3.pir SKA_COMPLEX SKA Ska1 PTHR28573.mag.mod SPINDLE_AND_KINETOCHORE-ASSOCIATED_PROTEIN_1 PTHR28573.orig.30.pir SKA_COMPLEX SKA Ska1 PTHR28573.SF1.mod SPINDLE_AND_KINETOCHORE-ASSOCIATED_PROTEIN_1 PTHR28573.SF1.pir SKA_COMPLEX SKA Ska2 PTHR32017.mag.mod SPINDLE_AND_KINETOCHORE-ASSOCIATED_PROTEIN_2 PTHR32017.orig.30.pir SKA_COMPLEX SKA Ska2 PTHR32017.SF3.mod SPINDLE_AND_KINETOCHORE-ASSOCIATED_PROTEIN_2 PTHR32017.SF3.pir SKA_COMPLEX SKA Ska3 PTHR48118.mag.mod SPINDLE_AND_KINETOCHORE-ASSOCIATED_PROTEIN_3 PTHR48118.orig.30.pir SKA_COMPLEX SKA Ska3 PTHR48118.SF1.mod SPINDLE_AND_KINETOCHORE-ASSOCIATED_PROTEIN_3 PTHR48118.SF1.pir DAM_COMPLEX DAM1-DASH Dam1 PTHR28113.mag.mod DASH_COMPLEX_SUBUNIT_DAM1 PTHR28113.orig.30.pir DAM_COMPLEX DAM1-DASH Dam1 PTHR28113.SF1.mod DASH_COMPLEX_SUBUNIT_DAM1 PTHR28113.SF1.pir DAM_COMPLEX DAM1-DASH Duo1 PTHR28216.mag.mod DASH_COMPLEX_SUBUNIT_DUO1 PTHR28216.orig.30.pir DAM_COMPLEX DAM1-DASH Duo1 PTHR28216.SF1.mod DASH_COMPLEX_SUBUNIT_DUO1 PTHR28216.SF1.pir DAM_COMPLEX DAM1-DASH Hsk3 PTHR28289.mag.mod DASH_COMPLEX_SUBUNIT_HSK3 PTHR28289.orig.30.pir DAM_COMPLEX DAM1-DASH Hsk3 PTHR28289.SF1.mod DASH_COMPLEX_SUBUNIT_HSK3 PTHR28289.SF1.pir DAM_COMPLEX DAM1-DASH Ask1 PTHR28200.mag.mod DASH_COMPLEX_SUBUNIT_ASK1 PTHR28200.orig.30.pir DAM_COMPLEX DAM1-DASH Ask1 PTHR28200.SF1.mod DASH_COMPLEX_SUBUNIT_ASK1 PTHR28200.SF1.pir DAM_COMPLEX DAM1-DASH Spc19 PTHR28262.mag.mod DASH_COMPLEX_SUBUNIT_SPC19 PTHR28262.orig.30.pir DAM_COMPLEX DAM1-DASH Spc19 PTHR28262.SF1.mod DASH_COMPLEX_SUBUNIT_SPC19 PTHR28262.SF1.pir DAM_COMPLEX DAM1-DASH Dad1 PTHR28025.mag.mod DASH_COMPLEX_SUBUNIT_DAD1 PTHR28025.orig.30.pir DAM_COMPLEX DAM1-DASH Dad1 PTHR28025.SF1.mod DASH_COMPLEX_SUBUNIT_DAD1 PTHR28025.SF1.pir DAM_COMPLEX DAM1-DASH Dad2 PTHR28036.mag.mod DASH_COMPLEX_SUBUNIT_DAD2 PTHR28036.orig.30.pir DAM_COMPLEX DAM1-DASH Dad2 PTHR28036.SF1.mod DASH_COMPLEX_SUBUNIT_DAD2 PTHR28036.SF1.pir DAM_COMPLEX DAM1-DASH Dad3 PTHR28017.mag.mod DASH_COMPLEX_SUBUNIT_DAD3 PTHR28017.orig.30.pir DAM_COMPLEX DAM1-DASH Dad3 PTHR28017.SF1.mod DASH_COMPLEX_SUBUNIT_DAD3 PTHR28017.SF1.pir DAM_COMPLEX DAM1-DASH Dad4 PTHR28222.mag.mod DASH_COMPLEX_SUBUNIT_DAD4 PTHR28222.orig.30.pir DAM_COMPLEX DAM1-DASH Dad4 PTHR28222.SF1.mod DASH_COMPLEX_SUBUNIT_DAD4 PTHR28222.SF1.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-platform Apc1 PTHR12827.SF3.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_1 PTHR12827.SF3.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-platform Apc1 PTHR12827.SF5.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_1 PTHR12827.SF5.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-platform Apc4 PTHR13260.mag.mod ANAPHASE_PROMOTING_COMPLEX_SUBUNIT_4__APC4 PTHR13260.orig.30.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-platform Apc4 PTHR13260.SF0.mod ANAPHASE_PROMOTING_COMPLEX_SUBUNIT_4__APC4 PTHR13260.SF0.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-platform Apc5 PTHR12830.mag.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_5 PTHR12830.orig.30.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-platform Apc5 PTHR12830.SF9.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_5 PTHR12830.SF9.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-platform Apc15 PTHR22526.SF4.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_15 PTHR22526.SF4.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-arc Apc3 PTHR12558.SF13.mod CELL_DIVISION_CYCLE_PROTEIN_27_HOMOLOG PTHR12558.SF13.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-arc Apc6 PTHR12558.SF9.mod CELL_DIVISION_CYCLE_PROTEIN_16_HOMOLOG PTHR12558.SF9.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-arc Apc8 PTHR12558.SF10.mod CELL_DIVISION_CYCLE_PROTEIN_23_HOMOLOG PTHR12558.SF10.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-arc Apc12 PTHR28579.mag.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_CDC26 PTHR28579.orig.30.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-arc Apc12 PTHR28579.SF1.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_CDC26 PTHR28579.SF1.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-arc Apc13 PTHR28672.mag.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_13 PTHR28672.orig.30.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-arc Apc13 PTHR28672.SF1.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_13 PTHR28672.SF1.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-catalytic_core Apc2 PTHR45957.mag.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_2 PTHR45957.orig.30.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-catalytic_core Apc2 PTHR45957.SF1.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_2 PTHR45957.SF1.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-catalytic_core Apc10 PTHR12936.mag.mod ANAPHASE-PROMOTING_COMPLEX_10 PTHR12936.orig.30.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-catalytic_core Apc10 PTHR12936.SF0.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_10 PTHR12936.SF0.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-catalytic_core Apc11 PTHR11210.SF1.mod ANAPHASE-PROMOTING_COMPLEX_SUBUNIT_11 PTHR11210.SF1.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-catalytic_core Ube2s PTHR24068.SF126.mod UBC_CORE_DOMAIN-CONTAINING_PROTEIN PTHR24068.SF126.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-catalytic_core Ube2c PTHR24067.SF338.mod UBIQUITIN-CONJUGATING_ENZYME_E2C PTHR24067.SF338.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-co-activator Cdh1 PTHR19918.SF1.mod FIZZY-RELATED_PROTEIN_HOMOLOG PTHR19918.SF1.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-co-activator Cdc20 PTHR19918.SF8.mod WD_REPEAT-CONTAINING_PROTEIN_55_HOMOLOG PTHR19918.SF8.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-co-activator Cdc20 PTHR19918.SF5.mod MEIOSIS-SPECIFIC_APC-C_ACTIVATOR_PROTEIN_AMA1 PTHR19918.SF5.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-substrates Cyclin_A PTHR10177.SF472.mod G2/MITOTIC-SPECIFIC_CYCLIN-3-RELATED PTHR10177.SF472.pir ANAPHASE_PROMOTING_COMPLEX/CYCLOSOME APC-C-substrates Cyclin_B PTHR10177.SF559.mod G2/MITOTIC-SPECIFIC_CYCLIN-B PTHR10177.SF559.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Mad1 PTHR23168.mag.mod MITOTIC_SPINDLE_ASSEMBLY_CHECKPOINT_PROTEIN_MAD1__MITOTIC_ARREST_DEFICIENT-LIKE_PROTEIN_1 PTHR23168.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Mad1 PTHR23168.SF0.mod MITOTIC_SPINDLE_ASSEMBLY_CHECKPOINT_PROTEIN_MAD1__MITOTIC_ARREST_DEFICIENT-LIKE_PROTEIN_1 PTHR23168.SF0.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Mad2 PTHR11842.mag.mod MITOTIC_SPINDLE_ASSEMBLY_CHECKPOINT_PROTEIN_MAD2 PTHR11842.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Mad2 PTHR11842.SF11.mod MITOTIC_SPINDLE_ASSEMBLY_CHECKPOINT_PROTEIN_MAD2A PTHR11842.SF11.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC MadBub PTHR14030.mag.mod MITOTIC_CHECKPOINT_SERINE/THREONINE-PROTEIN_KINASE_BUB1 PTHR14030.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC MadBub PTHR14030.SF4.mod BUB1-RELATED_KINASE PTHR14030.SF4.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Mps1 PTHR22974.SF21.mod DUAL_SPECIFICITY_PROTEIN_KINASE_TTK PTHR22974.SF21.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Plk PTHR24345.SF92.mod SERINE/THREONINE-PROTEIN_KINASE_PLK PTHR24345.SF92.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Bub3 PTHR10971.mag.mod MRNA_EXPORT_FACTOR_AND_BUB3 PTHR10971.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Bub3 PTHR10971.SF5.mod MITOTIC_CHECKPOINT_PROTEIN_BUB3 PTHR10971.SF5.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC BugZ PTHR23215.mag.mod ZINC_FINGER_PROTEIN_207 PTHR23215.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC BugZ PTHR23215.SF1.mod BUB3-INTERACTING_AND_GLEBS_MOTIF-CONTAINING_PROTEIN_ZNF207 PTHR23215.SF1.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Zwint-1 PTHR31504.mag.mod ZW10_INTERACTOR_ZWINT PTHR31504.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Zwint-1 PTHR31504.SF1.mod ZW10_INTERACTOR PTHR31504.SF1.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Knl1 PTHR16520.mag.mod KINETOCHORE_SCAFFOLD_1 PTHR16520.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Knl1 PTHR16520.SF3.mod KINETOCHORE_SCAFFOLD_1 PTHR16520.SF3.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC ZW10 PTHR12205.mag.mod CENTROMERE/KINETOCHORE_PROTEIN_ZW10 PTHR12205.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC ZW10 PTHR12205.SF0.mod CENTROMERE/KINETOCHORE_PROTEIN_ZW10_HOMOLOG PTHR12205.SF0.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Zwilch PTHR15995.mag.mod PROTEIN_ZWILCH_HOMOLOG PTHR15995.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Zwilch PTHR15995.SF1.mod PROTEIN_ZWILCH_HOMOLOG PTHR15995.SF1.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Rod PTHR15688.mag.mod KINETOCHORE-ASSOCIATED_PROTEIN_1 PTHR15688.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Rod PTHR15688.SF1.mod KINETOCHORE-ASSOCIATED_PROTEIN_1 PTHR15688.SF1.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Trip13 PTHR45991.mag.mod PACHYTENE_CHECKPOINT_PROTEIN_2 PTHR45991.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC Trip13 PTHR45991.SF1.mod PACHYTENE_CHECKPOINT_PROTEIN_2_HOMOLOG PTHR45991.SF1.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC p31comet PTHR15681.mag.mod MAD2L1-BINDING_PROTEIN PTHR15681.orig.30.pir SPINDLE_ASSEMBLY_CHECKPOINT SAC p31comet PTHR15681.SF1.mod MAD2L1-BINDING_PROTEIN PTHR15681.SF1.pir
Replisome
ORIGIN_RECOGNITION_COMPLEX ORC Cdc6-Orc1 PTHR10763.mag.mod CELL_DIVISION_CONTROL_PROTEIN_6-RELATED PTHR10763.orig.30.pir ORIGIN_RECOGNITION_COMPLEX ORC Cdc6 PTHR10763.SF26.mod CELL_DIVISION_CONTROL_PROTEIN_6_HOMOLOG PTHR10763.SF26.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc1 PTHR10763.SF23.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_1 PTHR10763.SF23.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc2 PTHR14052.mag.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_2 PTHR14052.orig.30.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc2 PTHR14052.SF0.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_2 PTHR14052.SF0.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc3 PTHR12748.mag.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_3 PTHR12748.orig.30.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc3 PTHR12748.SF0.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_3 PTHR12748.SF0.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc3 PTHR12748.SF1.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_3 PTHR12748.SF1.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc4 PTHR12087.mag.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_4 PTHR12087.orig.30.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc4 PTHR12087.SF0.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_4 PTHR12087.SF0.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc5 PTHR12705.mag.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_5 PTHR12705.orig.30.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc5 PTHR12705.SF0.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_5 PTHR12705.SF0.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc6 PTHR13394.mag.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_6 PTHR13394.orig.30.pir ORIGIN_RECOGNITION_COMPLEX ORC Orc6 PTHR13394.SF0.mod ORIGIN_RECOGNITION_COMPLEX_SUBUNIT_6 PTHR13394.SF0.pir FIRING_ELONGATION_FACTORS FIRE Cdt1 PTHR28637.mag.mod DNA_REPLICATION_FACTOR_CDT1 PTHR28637.orig.30.pir FIRING_ELONGATION_FACTORS FIRE Cdt1 PTHR28637.SF1.mod DNA_REPLICATION_FACTOR_CDT1 PTHR28637.SF1.pir FIRING_ELONGATION_FACTORS FIRE Cdt1 PTHR28637.SF10.mod CDT1-LIKE_PROTEIN_B PTHR28637.SF10.pir FIRING_ELONGATION_FACTORS FIRE Cdt1 PTHR28637.SF12.mod CDT1_DOMAIN-CONTAINING_PROTEIN PTHR28637.SF12.pir FIRING_ELONGATION_FACTORS FIRE Mcm10 PTHR13454.mag.mod PROTEIN_MCM10_HOMOLOG PTHR13454.orig.30.pir FIRING_ELONGATION_FACTORS FIRE Mcm10 PTHR13454.SF11.mod PROTEIN_MCM10_HOMOLOG PTHR13454.SF11.pir FIRING_ELONGATION_FACTORS FIRE Cdc45 PTHR10507.mag.mod CDC45-RELATED_PROTEIN PTHR10507.orig.30.pir FIRING_ELONGATION_FACTORS FIRE Cdc45 PTHR10507.SF0.mod CELL_DIVISION_CONTROL_PROTEIN_45_HOMOLOG PTHR10507.SF0.pir FIRING_ELONGATION_FACTORS FIRE GMNN PTHR13372.mag.mod GEMININ PTHR13372.orig.30.pir FIRING_ELONGATION_FACTORS FIRE GMNN PTHR13372.SF2.mod GEMININ_COILED-COIL_DOMAIN-CONTAINING_PROTEIN_1 PTHR13372.SF2.pir FIRING_ELONGATION_FACTORS FIRE GMNN PTHR13372.SF5.mod GEMININ PTHR13372.SF5.pir FIRING_ELONGATION_FACTORS FIRE GMNN PTHR13372.SF4.mod GEMININ PTHR13372.SF4.pir DNA_REPLICATION_COMPLEX_GINS GINS PSF1 PTHR12914.mag.mod PARTNER_OF_SLD5 PTHR12914.orig.30.pir DNA_REPLICATION_COMPLEX_GINS GINS PSF1 PTHR12914.SF2.mod DNA_REPLICATION_COMPLEX_GINS_PROTEIN_PSF1 PTHR12914.SF2.pir DNA_REPLICATION_COMPLEX_GINS GINS PSF2 PTHR12772.mag.mod DNA_REPLICATION_COMPLEX_GINS_PROTEIN_PSF2 PTHR12772.orig.30.pir DNA_REPLICATION_COMPLEX_GINS GINS PSF2 PTHR12772.SF0.mod DNA_REPLICATION_COMPLEX_GINS_PROTEIN_PSF2 PTHR12772.SF0.pir DNA_REPLICATION_COMPLEX_GINS GINS PSF3 PTHR22768.mag.mod UNCHARACTERIZED PTHR22768.orig.30.pir DNA_REPLICATION_COMPLEX_GINS GINS PSF3 PTHR22768.SF0.mod DNA_REPLICATION_COMPLEX_GINS_PROTEIN_PSF3 PTHR22768.SF0.pir PROLIFERATING_CELL_NUCLEAR_ANTIGEN PCNA PCNA PTHR11352.mag.mod PROLIFERATING_CELL_NUCLEAR_ANTIGEN PTHR11352.orig.30.pir PROLIFERATING_CELL_NUCLEAR_ANTIGEN PCNA PCNA PTHR11352.SF0.mod PROLIFERATING_CELL_NUCLEAR_ANTIGEN PTHR11352.SF0.pir PROLIFERATING_CELL_NUCLEAR_ANTIGEN PCNA PCNA PTHR11352.SF5.mod PROLIFERATING_CELL_NUCLEAR_ANTIGEN PTHR11352.SF5.pir PROLIFERATING_CELL_NUCLEAR_ANTIGEN PCNA PCNA PTHR11352.SF6.mod PROLIFERATING_CELL_NUCLEAR_ANTIGEN PTHR11352.SF6.pir PROLIFERATING_CELL_NUCLEAR_ANTIGEN PCNA PCNA PTHR11352.SF8.mod PROLIFERATING_CELL_NUCLEAR_ANTIGEN PTHR11352.SF8.pir PROLIFERATING_CELL_NUCLEAR_ANTIGEN PCNA PCNA PTHR11352.SF10.mod PROLIFERATING_CELL_NUCLEAR_ANTIGEN_FAMILY_PROTEIN PTHR11352.SF10.pir PROLIFERATING_CELL_NUCLEAR_ANTIGEN PCNA PCNA PTHR11352.SF11.mod PROLIFERATING_CELL_NUCLEAR_ANTIGEN PTHR11352.SF11.pir PROLIFERATING_CELL_NUCLEAR_ANTIGEN PCNA PCNA PTHR11352.SF12.mod PROLIFERATING_CELL_NUCLEAR_ANTIGEN PTHR11352.SF12.pir PROLIFERATING_CELL_NUCLEAR_ANTIGEN PCNA PCNA PTHR11352.SF13.mod PROLIFERATING_CELL_NUCLEAR_ANTIGEN PTHR11352.SF13.pir MCM_HELICASE MCM Mcm2-7 PTHR11630.mag.mod DNA_REPLICATION_LICENSING_FACTOR_MCM_FAMILY_MEMBER PTHR11630.orig.30.pir MCM_HELICASE MCM Mcm2 PTHR11630.SF101.mod DNA_REPLICATION_LICENSING_FACTOR_MCM2 PTHR11630.SF101.pir MCM_HELICASE MCM Mcm2 PTHR11630.SF44.mod DNA_REPLICATION_LICENSING_FACTOR_MCM2 PTHR11630.SF44.pir MCM_HELICASE MCM Mcm3 PTHR11630.SF46.mod DNA_REPLICATION_LICENSING_FACTOR_MCM3 PTHR11630.SF46.pir MCM_HELICASE MCM Mcm4 PTHR11630.SF66.mod DNA_REPLICATION_LICENSING_FACTOR_MCM4 PTHR11630.SF66.pir MCM_HELICASE MCM Mcm5 PTHR11630.SF42.mod DNA_REPLICATION_LICENSING_FACTOR_MCM5 PTHR11630.SF42.pir MCM_HELICASE MCM Mcm6 PTHR11630.SF43.mod DNA_REPLICATION_LICENSING_FACTOR_MCM6 PTHR11630.SF43.pir MCM_HELICASE MCM Mcm6 PTHR11630.SF73.mod DNA_REPLICATION_LICENSING_FACTOR_MCM6 PTHR11630.SF73.pir MCM_HELICASE MCM Mcm7 PTHR11630.SF105.mod DNA_REPLICATION_LICENSING_FACTOR_MCM7 PTHR11630.SF105.pir MCM_HELICASE MCM Mcm7 PTHR11630.SF26.mod DNA_REPLICATION_LICENSING_FACTOR_MCM7 PTHR11630.SF26.pir CDC7_DB4 CDC7_DB4 Cdc7 PTHR44167.mag.mod OVARIAN-SPECIFIC_SERINE/THREONINE-PROTEIN_KINASE_LOK-RELATED PTHR44167.orig.30.pir CDC7_DB4 CDC7_DB4 Cdc7 PTHR44167.SF23.mod CDC7_KINASE,_ISOFORM_A-RELATED PTHR44167.SF23.pir CDC7_DB4 CDC7_DB4 Db4 PTHR15375.mag.mod ACTIVATOR_OF_S-PHASE_KINASE-RELATED PTHR15375.orig.30.pir CDC7_DB4 CDC7_DB4 Db4a PTHR15375.SF22.mod PROTEIN_DBF4_HOMOLOG_A PTHR15375.SF22.pir CDC7_DB4 CDC7_DB4 Db4b PTHR15375.SF24.mod PROTEIN_DBF4_HOMOLOG_B PTHR15375.SF24.pir REPLICATION_FACTOR_A RFA RFA1 PTHR23273.mag.mod REPLICATION_FACTOR_A_1,_RFA1 PTHR23273.orig.30.pir REPLICATION_FACTOR_A RFA RFA1 PTHR23273.SF47.mod REPLICATION_PROTEIN_A_70_KDA_DNA-BINDING_SUBUNIT_A PTHR23273.SF47.pir REPLICATION_FACTOR_A RFA RFA2 PTHR13989.SF43.mod REPLICATION_PROTEIN_A_30_KDA_SUBUNIT-RELATED PTHR13989.SF43.pir REPLICATION_FACTOR_A RFA RFA3 PTHR47058.mag.mod REPLICATION_PROTEIN_A_14_KDA_SUBUNIT_A-RELATED PTHR47058.orig.30.pir REPLICATION_FACTOR_A RFA RFA3 PTHR47058.SF3.mod REPLICATION_PROTEIN_A_14_KDA_SUBUNIT_A-RELATED PTHR47058.SF3.pir REPLICATION_FACTOR_C RFC RFC1 PTHR23389.SF6.mod REPLICATION_FACTOR_C_SUBUNIT_1 PTHR23389.SF6.pir REPLICATION_FACTOR_C RFC RFC2 PTHR11669.SF5.mod REPLICATION_FACTOR_C_SUBUNIT_2 PTHR11669.SF5.pir REPLICATION_FACTOR_C RFC RFC3 PTHR11669.SF1.mod REPLICATION_FACTOR_C_SUBUNIT_3 PTHR11669.SF1.pir REPLICATION_FACTOR_C RFC RFC4 PTHR11669.SF20.mod REPLICATION_FACTOR_C_SUBUNIT_4 PTHR11669.SF20.pir REPLICATION_FACTOR_C RFC RFC5 PTHR11669.SF9.mod REPLICATION_FACTOR_C_SUBUNIT_5 PTHR11669.SF9.pir DNA_POLYMERASE_ALPHA POLA PolA1 PTHR45861.mag.mod DNA_POLYMERASE_ALPHA_CATALYTIC_SUBUNIT PTHR45861.orig.30.pir DNA_POLYMERASE_ALPHA POLA PolA1 PTHR45861.SF1.mod DNA_POLYMERASE_ALPHA_CATALYTIC_SUBUNIT PTHR45861.SF1.pir DNA_POLYMERASE_ALPHA POLA PolA2 PTHR23061.mag.mod DNA_POLYMERASE_2_ALPHA_70_KDA_SUBUNIT PTHR23061.orig.30.pir DNA_POLYMERASE_ALPHA POLA PolA2 PTHR23061.SF12.mod DNA_POLYMERASE_ALPHA_SUBUNIT_B PTHR23061.SF12.pir DNA_PRIMASE PRIM Prim1 PTHR10536.mag.mod DNA_PRIMASE_SMALL_SUBUNIT PTHR10536.orig.30.pir DNA_PRIMASE PRIM Prim1 PTHR10536.SF0.mod DNA_PRIMASE_SMALL_SUBUNIT PTHR10536.SF0.pir DNA_PRIMASE PRIM Prim2 PTHR10537.mag.mod DNA_PRIMASE_LARGE_SUBUNIT PTHR10537.orig.30.pir DNA_PRIMASE PRIM Prim2 PTHR10537.SF3.mod DNA_PRIMASE_LARGE_SUBUNIT PTHR10537.SF3.pir DNA_PRIMASE PRIM Prim2 PTHR10537.SF6.mod DNA_PRIMASE_LARGE_SUBUNIT PTHR10537.SF6.pir DNA_POLYMERASE_DELTA POLD PolD1 PTHR10322.mag.mod DNA_POLYMERASE_CATALYTIC_SUBUNIT PTHR10322.orig.30.pir DNA_POLYMERASE_DELTA POLD PolD1 PTHR10322.SF23.mod DNA_POLYMERASE_DELTA_CATALYTIC_SUBUNIT PTHR10322.SF23.pir DNA_POLYMERASE_DELTA POLD PolD2 PTHR10416.mag.mod DNA_POLYMERASE_DELTA_SUBUNIT_2 PTHR10416.orig.30.pir DNA_POLYMERASE_DELTA POLD PolD2 PTHR10416.SF0.mod DNA_POLYMERASE_DELTA_SUBUNIT_2 PTHR10416.SF0.pir DNA_POLYMERASE_DELTA POLD PolD3 PTHR17598.mag.mod DNA_POLYMERASE_DELTA_SUBUNIT_3 PTHR17598.orig.30.pir DNA_POLYMERASE_DELTA POLD PolD3 PTHR17598.SF13.mod DNA_POLYMERASE_DELTA_SUBUNIT_3 PTHR17598.SF13.pir DNA_POLYMERASE_DELTA POLD PolD4 PTHR14303.mag.mod DNA_POLYMERASE_DELTA_SUBUNIT_4 PTHR14303.orig.30.pir DNA_POLYMERASE_DELTA POLD PolD4 PTHR14303.SF0.mod DNA_POLYMERASE_DELTA_SUBUNIT_4 PTHR14303.SF0.pir DNA_POLYMERASE_EPSILON POLE PolE1 PTHR10670.mag.mod DNA_POLYMERASE_EPSILON_CATALYTIC_SUBUNIT_A PTHR10670.orig.30.pir DNA_POLYMERASE_EPSILON POLE PolE1 PTHR10670.SF0.mod DNA_POLYMERASE_EPSILON_CATALYTIC_SUBUNIT_A PTHR10670.SF0.pir DNA_POLYMERASE_EPSILON POLE PolE2 PTHR12708.mag.mod DNA_POLYMERASE_EPSILON_SUBUNIT_B PTHR12708.orig.30.pir DNA_POLYMERASE_EPSILON POLE PolE3 PTHR46172.mag.mod DNA_POLYMERASE_EPSILON_SUBUNIT_3 PTHR46172.orig.30.pir DNA_POLYMERASE_EPSILON POLE PolE3 PTHR46172.SF1.mod DNA_POLYMERASE_EPSILON_SUBUNIT_3 PTHR46172.SF1.pir DNA_POLYMERASE_EPSILON POLE PolE4 PTHR10252.SF79.mod DNA_POLYMERASE_EPSILON_SUBUNIT_4 PTHR10252.SF79.pir
Sexual reproduction / Meiosis ?
CATSPER_COMPLEX CATSPER CatSper-g PTHR14327.mag.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_SUBUNIT_GAMMA PTHR14327.orig.30.pir CATSPER_COMPLEX CATSPER CatSper-g PTHR14327.SF1.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_SUBUNIT_GAMMA PTHR14327.SF1.pir CATSPER_COMPLEX CATSPER CatSper-b PTHR14705.mag.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_SUBUNIT_BETA PTHR14705.orig.30.pir CATSPER_COMPLEX CATSPER CatSper-b PTHR14705.SF0.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_SUBUNIT_BETA PTHR14705.SF0.pir CATSPER_COMPLEX CATSPER CatSper-d PTHR33722.mag.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_SUBUNIT_DELTA-RELATED PTHR33722.orig.30.pir CATSPER_COMPLEX CATSPER CatSper-e PTHR33722.SF3.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_SUBUNIT_EPSILON PTHR33722.SF3.pir CATSPER_COMPLEX CATSPER CatSper-d PTHR33722.SF1.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_SUBUNIT_DELTA PTHR33722.SF1.pir CATSPER_COMPLEX CATSPER CatSper-z PTHR42155.mag.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_SUBUNIT_ZETA PTHR42155.orig.30.pir CATSPER_COMPLEX CATSPER CatSper-z PTHR42155.SF1.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_SUBUNIT_ZETA PTHR42155.SF1.pir CATSPER_COMPLEX CATSPER CatSper-2 PTHR46923.mag.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_2 PTHR46923.orig.30.pir CATSPER_COMPLEX CATSPER CatSper-2 PTHR46923.SF1.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_2 PTHR46923.SF1.pir CATSPER_COMPLEX CATSPER CatSper-4 PTHR47077.SF1.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_4 PTHR47077.SF1.pir CATSPER_COMPLEX CATSPER CatSper-3 PTHR47131.mag.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_3 PTHR47131.orig.30.pir CATSPER_COMPLEX CATSPER CatSper-3 PTHR47131.SF1.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_3 PTHR47131.SF1.pir CATSPER_COMPLEX CATSPER CatSper-1 PTHR47193.mag.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_1 PTHR47193.orig.30.pir CATSPER_COMPLEX CATSPER CatSper-1 PTHR47193.SF1.mod CATION_CHANNEL_SPERM-ASSOCIATED_PROTEIN_1 PTHR47193.SF1.pir CAMP_SIGNALING_TMCB TMCB tmcB PTHR31600.mag.mod TINY_MACROCYSTS_PROTEIN_B-RELATED PTHR31600.orig.30.pir CAMP_SIGNALING_TMCB TMCB tmcB PTHR31600.SF2.mod TINY_MACROCYSTS_PROTEIN_B-RELATED PTHR31600.SF2.pir GAMETE_EXPRESSION GEX1 gex1 PTHR33538.mag.mod PROTEIN_GAMETE_EXPRESSED_1 PTHR33538.orig.30.pir GAMETE_EXPRESSION GEX1 gex1 PTHR33538.SF2.mod PROTEIN_GAMETE_EXPRESSED_1 PTHR33538.SF2.pir MEMBRANE_FUSION_BETWEEN_GAMETES HAP2 hap2 PTHR31764.mag.mod PROTEIN_HAPLESS_2 PTHR31764.orig.30.pir MEMBRANE_FUSION_BETWEEN_GAMETES HAP2 hap2 PTHR31764.SF0.mod HAP2-GCS1_DOMAIN-CONTAINING_PROTEIN PTHR31764.SF0.pir
Polyadenylation machinery
POLYA_MACHINERY CPSF CPSF1/CPSF160 PTHR10644.mag.mod DNA REPAIR/RNA PROCESSING CPSF FAMILY POLYA_MACHINERY CPSF CPSF1/CPSF160 PTHR10644.SF2.mod CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 POLYA_MACHINERY CPSF CPSF1/CPSF160 PTHR10644.SF6.mod CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR (CPSF) A SUBUNIT PROTEIN POLYA_MACHINERY CPSF CPSF2/CPSF100 PTHR45922.mag.mod CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 POLYA_MACHINERY CPSF CPSF2/CPSF100 PTHR45922.SF1.mod CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 POLYA_MACHINERY CPSF CPSF3/CPSF73 PTHR11203.mag.mod CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER POLYA_MACHINERY CPSF CPSF3/CPSF73 PTHR11203.SF11.mod CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3 POLYA_MACHINERY CPSF CPSF4/CPSF30 PTHR23102.mag.mod CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED POLYA_MACHINERY CPSF CPSF4/CPSF30 PTHR23102.SF18.mod CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4 POLYA_MACHINERY CstF CstF1/CstF50 PTHR44133.mag.mod CLEAVAGE STIMULATION FACTOR SUBUNIT 1 POLYA_MACHINERY CstF CstF1/CstF50 PTHR44133.SF2.mod CLEAVAGE STIMULATION FACTOR SUBUNIT 1 POLYA_MACHINERY CstF CstF2/CstF64 PTHR45735.mag.mod CLEAVAGE STIMULATION FACTOR SUBUNIT 2 POLYA_MACHINERY CstF CstF2/CstF64 PTHR45735.SF6.mod CLEAVAGE STIMULATION FACTOR SUBUNIT 2 POLYA_MACHINERY CstF CstF3/CstF77 PTHR19980.mag.mod RNA CLEAVAGE STIMULATION FACTOR POLYA_MACHINERY CstF CstF3/CstF77 PTHR19980.SF0.mod CLEAVAGE STIMULATION FACTOR SUBUNIT 3 POLYA_MACHINERY other Fip1 PTHR13484.mag.mod FIP1-LIKE 1 PROTEIN POLYA_MACHINERY other Fip1 PTHR13484.SF9.mod PRE-MRNA 3'-END-PROCESSING FACTOR FIP1 POLYA_MACHINERY other WDR33 PTHR22836.mag.mod WD40 REPEAT PROTEIN POLYA_MACHINERY other WDR33 PTHR22836.SF0.mod PRE-MRNA 3' END PROCESSING PROTEIN WDR33
finding_genes_of_interest_with_panther_hmms.1769098536.txt.gz · Last modified: by 172.20.120.170